Excellent Response to Lower Dose of 177Lu-PSMA-617 in a Metastatic Castration-Resistant Prostate Cancer Patient With a Transplanted Kidney

被引：5

作者：

Norouzi, Ghazal ^{[1
]}

Aghdam, Ramin Akbarian ^{[1
]}

Hashemifard, Hamidreza ^{[2
]}

Pirayesh, Elahe ^{[1
]}

机构：

[1] Shahid Beheshti Univ Med Sci, Dept Nucl Med, Shohada & Tajrish Med Ctr, Sch Med, Tehran, Iran

[2] Gandi Hosp, Dept Radiat Oncol, Tehran, Iran

来源：

CLINICAL NUCLEAR MEDICINE | 2019年 / 44卷 / 06期

关键词：

Lu-177-PSMA-617; prostate cancer; radioligand therapy; nephrotoxicity; kidney transplant; LU-177-PSMA-617 RADIOLIGAND THERAPY;

D O I：

10.1097/RLU.0000000000002508

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

A 68-year-old man with metastatic castration-resistant prostate cancer and widespread bone metastases as well as a history of kidney transplant, underwent 5 cycles of Lu-177-prostate-specific membrane antigen 617 therapies in our department. Being more cautious of the radiation burden imposed on the transplanted kidney, a lower average dose of 4 GBq per cycle was administered (instead of the more routine 6.0-7.4 GBq per cycle). However, excellent response was noted and serum creatinine level of 0.8 mg/dL remained stable.

引用

页码：483 / 484

页数：2

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