Comparing anesthetic efficacy of articaine versus lidocaine as a supplemental buccal infiltration of the mandibular first molar after an inferior alveolar nerve block

被引:68
作者
Haase, Andrew
Reader, Al [1 ]
Nusstein, John [1 ]
Beck, Mike [2 ]
Drum, Melissa [1 ]
机构
[1] Ohio State Univ, Div Endodont, Coll Dent, Columbus, OH 43210 USA
[2] Ohio State Univ, Div Oral Biol, Columbus, OH 43210 USA
关键词
local anesthetics; articaine; lidocaine; infiltration; inferior alveolar nerve block;
D O I
10.14219/jada.archive.2008.0338
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Background. The authors conducted a prospective randomized, double-blind, crossover study Comparing the degree of pulpal anesthesia achieved by means of mandibular first molar buccal infiltrations of two anesthetic solutions: 4 percent articaine with 1:100,000 epinephrine and 2 percent lidocaine with 1:100,000000 eepinephrine after an inferior alveolar nerve (IAN) block with the use of 4 percent articaine with 1:100,000 epinephrine. Methods. Seventy-three blinded adult subjects randomly received buccal infiltrations at the first molar site with a cartridge of 4 percent articaine with 1:100,000 epinephrine at one appointment and a cartridge of 2 percent lidocaine with 1:100,000 epinephrine at another appointment after receiving a standard LAN block with the use of 4 percent articaine with 1:100,000 epinephrine in a crossover design. After the injections, the authors used an electric pulp tester to test the first molar for anesthesia in three-minute cycles for 60 minutes. They considered anesthesia to be successful when two consecutive 80 readings were obtained within 10 minutes of the LAN block and infiltration injection, and the 80 reading was sustained continuously through the 60th minute. Results. The authors found that with the use of the 4 percent articaine formulation, successful pulpal anesthesia occurred 88 percent of the time for the first molar. With the 2 percent lidocaine formulation, successful pulpal anesthesia occurred 71 percent of the time. The results show a significant difference (P <.05) between the articaine and lidocaine formulations. Conclusion and Clinical implications. For a mandibular buccal infiltration of the first molar after a standard LAN block, 4 percent articaine with 1:100,000 epinephrine resulted in a higher success rate (88 percent) than did 2 percent lidocaine with 1:100,000 epinephrine (71 percent success rate).
引用
收藏
页码:1228 / 1235
页数:8
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