Extracorporeal life support as a bridge to lung transplantation: Where are we now?

被引:8
作者
Patterson, Caroline M. [1 ]
Shah, Aakash [2 ]
Rabin, Joseph [2 ]
DiChiacchio, Laura [2 ]
Cypel, Marcelo [3 ]
Hoetzenecker, Konrad [4 ]
Catarino, Pedro [5 ]
Lau, Christine L. [2 ]
机构
[1] Royal Papworth Hosp, Transplant Continuing Care Unit Unit, Cambridge, England
[2] Univ Maryland, Sch Med, Dept Surg, Baltimore, MD USA
[3] Univ Toronto, Univ Hlth Network, Div Thorac Surg, Dept Surg, Toronto, ON, Canada
[4] Med Univ Vienna, Dept Thorac Surg, Vienna, Austria
[5] Smidt Heart Inst, Cedars Sinai, Los Angeles, CA USA
关键词
extracorporeal life support; extracorporeal membrane oxygenation; bridge to transplant; cannulation; extracorporeal carbon dioxide removal; MEMBRANE-OXYGENATION; EXPERIENCE; ASSIST; COVID-19; EFFICACY; CANNULA; VOLUME; ARTERY;
D O I
10.1016/j.healun.2022.06.004
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The number of lung transplant procedures performed internationally is increasing but the donor organ pool is insufficient to meet demand and waiting list mortality is unacceptably high. As survival rates for patients with acute respiratory distress syndrome managed on extracorporeal life support (ECLS) have steadily improved, a potential role for ECLS to support critically ill patients awaiting a donor organ match has emerged. We explore the rapidly evolving landscape of ECLS as a bridge to lung transplantation with review of the patient selection criteria, predictors of survival, modes of pre and peri-transplant support, and the importance of a holistic multidisciplinary approach to care. Finally, we consider innovations that are envisaged to increase the accessibility, safety, and effectiveness of ECLS delivery for future lung transplant candidates. (C) 2022 International Society for Heart and Lung Transplantation. All rights reserved.
引用
收藏
页码:1547 / 1555
页数:9
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