1H NMR Relaxation Study of a Magnetic Ionic Liquid as a Potential Contrast Agent

被引:22
作者
Daniel, Carla I. [1 ]
Vaca Chavez, Fabian [2 ]
Portugal, Carla A. M. [1 ]
Crespo, Joao G. [1 ]
Sebastiao, Pedro J. [3 ]
机构
[1] Univ Nova Lisboa, Fac Ciencias & Tecnol, Dept Quim, REQUIMTE LAQV, P-1200 Lisbon, Portugal
[2] Univ Nacl Cordoba, FAMAF, IFEG CONICET, Cordoba, Argentina
[3] Univ Lisbon, Inst Super Tecn, Dept Fis, Ctr Phys & Engn Adv Mat, P-1699 Lisbon, Portugal
关键词
TRANSITION; NANOPARTICLES; RELAXOMETRY; COMPLEXES;
D O I
10.1021/acs.jpcb.5b04772
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
A proton nuclear magnetic relaxation dispersion H-1 NMRD study of the molecular dynamics in mixtures of magnetic ionic liquid [P-66614] [FeCl4] with [P-66614] [Cl] ionic liquid and mixtures of [P-66614] [PeCl(4)] with dimethyl sulfoxide (DMSO) is presented. The proton spin-lattice relaxation rate, R-1, was measured in the frequency range of 8 kHz-300 MHz. The viscosity of the binary mixtures was measured as a function of an applied magnetic field, B, in the range of 0-2 T. In the case of DMSO/[P-66614][FeCl4] the viscosity was found to be independent from the magnetic field, while in the case of the [P-66614][Cl]/[P-66614][FeCl4] system viscosity decreased with the increase of the magnetic field strength. The spin-lattice relaxation results were analyzed for all systems taking into account the relaxation mechanisms associated with the molecular motions with correlation times in a range between 10(-11) and 10(-7)s, usually observed by NMRD, and the paramagnetic relaxation contributions associated with the presence of the magnetic ions in the systems. In the case of the DMSO/[P-66614] [FeCl4] system the R-1 dispersion shows relaxation enhancement due to the presence of the magnetic ions, similar to that reported for contrast agents. For the [P-66614] [Cl]/[P-66614] [FeCl4] system, the R-1 dispersion presents a much larger paramagnetic relaxation contribution, in comparison with that observed for the DMSO/[P-66614] [FeCl4] mixtures but different from that reported for other magnetic ionic liquid system. In the [P-66614] [Cl]/[P-66614] [FeCl4] system the relaxation enhancement associated with the paramagnetic ions is clearly not proportional to the concentration of magnetic ions, in contrast with what is observed for the DMSO/[P-66614] [PeCl(4)] system.
引用
收藏
页码:11740 / 11747
页数:8
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