Dielectrophoretic manipulation of drops for high-speed microfluidic sorting devices

被引:378
作者
Ahn, K
Kerbage, C
Hunt, TP
Westervelt, RM
Link, DR
Weitz, DA [1 ]
机构
[1] Harvard Univ, DEAS, Cambridge, MA 02138 USA
[2] Harvard Univ, Dept Phys, Cambridge, MA 02138 USA
[3] RainDance Technol, Guilford, CT 06437 USA
基金
美国国家科学基金会;
关键词
D O I
10.1063/1.2164911
中图分类号
O59 [应用物理学];
学科分类号
摘要
We demonstrate a high-throughput drop sorter for microfluidic devices that uses dielectrophoretic forces. Microelectrodes underneath a polydimethylsiloxane channel produce forces of more than 10 nN on a water drop in an inert oil, resulting in sorting rates greater than 1.6 kHz. We investigate the dependence of such forces on drop size and flow. Alternate designs with electrodes on either side of a symmetric channel Y junction provide refined control over droplet selection.
引用
收藏
页码:1 / 3
页数:3
相关论文
共 17 条
[1]   Formation of dispersions using "flow focusing" in microchannels [J].
Anna, SL ;
Bontoux, N ;
Stone, HA .
APPLIED PHYSICS LETTERS, 2003, 82 (03) :364-366
[2]   An integrated microfluidic system for reaction, high-sensitivity detection, and sorting of fluorescent cells and particles [J].
Dittrich, PS ;
Schwille, P .
ANALYTICAL CHEMISTRY, 2003, 75 (21) :5767-5774
[3]   An integrated microfabricated cell sorter [J].
Fu, AY ;
Chou, HP ;
Spence, C ;
Arnold, FH ;
Quake, SR .
ANALYTICAL CHEMISTRY, 2002, 74 (11) :2451-2457
[4]   Addressable micropost array for the dielectrophoretic manipulation of particles in fluid [J].
Hunt, TP ;
Lee, H ;
Westervelt, RM .
APPLIED PHYSICS LETTERS, 2004, 85 (26) :6421-6423
[5]  
KAWANO T, 2004, UNP P 8 INT C MIN SY
[6]  
LEE H, 2005, UNP IEEE INT SOL STA
[7]   Geometrically mediated breakup of drops in microfluidic devices [J].
Link, DR ;
Anna, SL ;
Weitz, DA ;
Stone, HA .
PHYSICAL REVIEW LETTERS, 2004, 92 (05) :4-545034
[8]  
McDonald JC, 2000, ELECTROPHORESIS, V21, P27, DOI 10.1002/(SICI)1522-2683(20000101)21:1<27::AID-ELPS27>3.0.CO
[9]  
2-C
[10]  
Pohl, 1978, DIELECTROPHORESIS