Diagnosis of Spontaneous Canine Hyperadrenocorticism: 2012 ACVIM Consensus Statement (Small Animal)

被引:172
作者
Behrend, E. N. [1 ]
Kooistra, H. S. [2 ]
Nelson, R. [3 ]
Reusch, C. E. [4 ]
Scott-Moncrieff, J. C. [5 ]
机构
[1] Auburn Univ, Coll Vet Med, Dept Clin Sci, Auburn, AL 36849 USA
[2] Univ Utrecht, Fac Vet Med, Dept Clin Sci Compan Anim, Utrecht, Netherlands
[3] Univ Calif Davis, Sch Vet Med, Dept Med & Epidemiol, Davis, CA 95616 USA
[4] Univ Zurich, Vetsuisse Fac, Clin Small Anim Internal Med, Zurich, Switzerland
[5] Purdue Univ, Dept Vet Clin Sci, Coll Vet Med, W Lafayette, IN 47907 USA
关键词
Adrenal cortex; Cushing's syndrome; Dog; Pituitary; PITUITARY-DEPENDENT HYPERADRENOCORTICISM; CLINICALLY NORMAL DOGS; ADRENOCORTICOTROPIC HORMONE STIMULATION; DEXAMETHASONE-SUPPRESSION TEST; PLASMA-CORTISOL CONCENTRATIONS; ENDOGENOUS ACTH CONCENTRATION; CONCURRENT DIABETES-MELLITUS; CUSHINGS-SYNDROME; CREATININE RATIO; COMPUTED-TOMOGRAPHY;
D O I
10.1111/jvim.12192
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
This report offers a consensus opinion on the diagnosis of spontaneous canine hyperadrenocorticism. The possibility that a patient has hyperadrenocorticism is based on the history and physical examination. Endocrine tests should be performed only when clinical signs consistent with HAC are present. None of the biochemical screening or differentiating tests for hyperadrenocorticism are perfect. Imaging can also play a role. Awareness of hyperadrenocorticism has heightened over time. Thus, case presentation is more subtle. Due to the changes in manifestations as well as test technology the Panel believes that references ranges should be reestablished. The role of cortisol precursors and sex hormones in causing a syndrome of occult hyperadrenocorticism remains unclear.
引用
收藏
页码:1292 / 1304
页数:13
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