Detection of human herpesvirus 6 and human herpesvirus 7 in the submandibular gland, parotid gland, and lip salivary gland by PCR

被引：59

作者：

Sada, E

Yasukawa, M

Ito, C

Takeda, A

Shiosaka, T

Tanioka, H

Fujita, S

机构：

[1] EHIME UNIV,SCH MED,DEPT INTERNAL MED 1,SHIGENOBU,EHIME 79102,JAPAN

[2] EHIME UNIV,SCH MED,DEPT ORAL & MAXILLOFACIAL SURG,SHIGENOBU,EHIME 79102,JAPAN

[3] JICHI MED SCH,DIV CLIN IMMUNOL,TOCHIGI,JAPAN

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 1996年 / 34卷 / 09期

关键词：

D O I：

10.1128/JCM.34.9.2320-2321.1996

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

In order to define the major sites of persistence of human herpesvirus 6 (HHV-6) and HHV-7, PCR with DNAs from more than 100 specimens of 3 different salivary glands was performed. HHV-6 DNA was detected in 52 (88.1%) of 59 submandibular gland, 17 (63.0%) of 27 parotid gland, and 9 (52.9%) of 17 lip salivary gland specimens. On the other hand, HHV-7 DNA was detected in 59 (100%) of 59 submandibular gland, 23 (85.2%) of 27 parotid gland, and 10 (58.8%) of 17 lip salivary gland specimens. These findings demonstrate that salivary glands are a site of persistent infection of both HHV-6 and HHV-7 and that among the three types of salivary gland examined, the submandibular gland is the primary one in which these herpesviruses, especially HHV-7, persist.

引用

收藏

页码：2320 / 2321

页数：2

相关论文

共 14 条

[1] HUMAN HERPESVIRUS-7 IS A T-LYMPHOTROPIC VIRUS AND IS RELATED TO, BUT SIGNIFICANTLY DIFFERENT FROM, HUMAN HERPESVIRUS-6 AND HUMAN CYTOMEGALOVIRUS [J].

BERNEMAN, ZN ;

ABLASHI, DV ;

LI, G ;

EGERFLETCHER, M ;

REITZ, MS ;

HUNG, CL ;

BRUS, I ;

KOMAROFF, AL ;

GALLO, RC .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (21) :10552-10556

[2] FREQUENT ISOLATION OF HUMAN HERPESVIRUS-7 FROM SALIVA [J].

BLACK, JB ;

INOUE, N ;

KITEPOWELL, K ;

ZAKI, S ;

PELLETT, PE .

VIRUS RESEARCH, 1993, 29 (01) :91-98

[3] HUMAN HERPESVIRUS-6 DNA IN PERIPHERAL-BLOOD CELLS AND SALIVA FROM IMMUNOCOMPETENT INDIVIDUALS [J].

CONE, RW ;

HUANG, MLW ;

ASHLEY, R ;

COREY, L .

JOURNAL OF CLINICAL MICROBIOLOGY, 1993, 31 (05) :1262-1267

[4] HUMAN HERPESVIRUSES 6 AND 7 IN SALIVARY-GLANDS AND SHEDDING IN SALIVA OF HEALTHY AND HUMAN-IMMUNODEFICIENCY-VIRUS POSITIVE INDIVIDUALS [J].

DILUCA, D ;

MIRANDOLA, P ;

RAVAIOLI, T ;

DOLCETTI, R ;

FRIGATTI, A ;

BOVENZI, P ;

SIGHINOLFI, L ;

MONINI, P ;

CASSAI, E .

JOURNAL OF MEDICAL VIROLOGY, 1995, 45 (04) :462-468

[5] HUMAN HERPESVIRUS-6 IN SALIVARY-GLANDS [J].

FOX, JD ;

BRIGGS, M ;

WARD, PA ;

TEDDER, RS .

LANCET, 1990, 336 (8715) :590-593

[6] FREQUENT SHEDDING OF HUMAN HERPESVIRUS-6 IN SALIVA [J].

HARNETT, GB ;

FARR, TJ ;

PIETROBONI, GR ;

BUCENS, MR .

JOURNAL OF MEDICAL VIROLOGY, 1990, 30 (02) :128-130

[7] FREQUENT ISOLATION OF HUMAN HERPESVIRUS-7 FROM SALIVA SAMPLES [J].

HIDAKA, Y ;

LIU, Y ;

YAMAMOTO, M ;

MORI, R ;

MIYAZAKI, C ;

KUSUHARA, K ;

OKADA, K ;

UEDA, K .

JOURNAL OF MEDICAL VIROLOGY, 1993, 40 (04) :343-346

[8] ASSOCIATION OF HUMAN HERPESVIRUS-6 INFECTION OF THE CENTRAL-NERVOUS-SYSTEM WITH RECURRENCE OF FEBRILE CONVULSIONS [J].

KONDO, K ;

NAGAFUJI, H ;

HATA, A ;

TOMOMORI, C ;

YAMANISHI, K .

JOURNAL OF INFECTIOUS DISEASES, 1993, 167 (05) :1197-1200

[9] LATENT HERPESVIRUS-6 IN SALIVARY AND BRONCHIAL GLANDS [J].

KRUEGER, GRF ;

WASSERMANN, K ;

DECLERCK, LS ;

STEVENS, WJ ;

BOURGEOIS, N ;

ABLASHI, DV ;

JOSEPHS, SF ;

BALACHANDRAN, N .

LANCET, 1990, 336 (8725) :1255-1256

[10] FREQUENT ISOLATION OF HHV-6 FROM SALIVA AND HIGH SEROPREVALENCE OF THE VIRUS IN THE POPULATION [J].

LEVY, JA ;

FERRO, F ;

GREENSPAN, D ;

LENNETTE, ET .

LANCET, 1990, 335 (8697) :1047-1050