Hydroxyalkyl Thiazolines, a New Class of Highly Efficient Ligands for Carbonyl Additions

被引：15

作者：

Bauer, Michael ^{[1
]}

Maurer, Erattke ^{[1
]}

Hoffmann, Svenja M. ^{[1
]}

Kazmaier, Uli ^{[1
]}

机构：

[1] Univ Saarland, Inst Organ Chem, D-66123 Saarbrucken, Germany

来源：

SYNLETT | 2008年 / 20期

关键词：

carbonyl additions; ligands; multicomponent reactions; nonlinear effect; thiazolines;

D O I：

10.1055/s-0028-1087366

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Hydroxyalkyl thiazoline ligands can easily be obtained in an isonitrile-based multicomponent reaction. These ligands are significantly more stable than the comparable oxazoline ligands, and give excellent enantiomeric excess in carbonyl additions or alkyl- and arylzinc compounds.

引用

页码：3203 / 3207

页数：5

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