A multidisciplinary approach to giant cell tumors of tendon sheath and synoviumA critical appraisal of literature and treatment proposal

被引：47

作者：

van der Heijden, Lizz ^{[1
]}

Gibbons, C. L. Max H. ^{[2
]}

Hassan, A. Bass ^{[3
]}

Kroep, Judith R. ^{[4
]}

Gelderblom, Hans ^{[4
]}

van Rijswijk, Carla S. P. ^{[5
]}

Nout, Remi A. ^{[4
]}

Bradley, Kevin M. ^{[6
]}

Athanasou, Nick A. ^{[7
]}

Dijkstra, P. D. Sander ^{[1
]}

Hogendoorn, Pancras C. W. ^{[8
]}

van de Sande, Michiel A. J. ^{[1
]}

机构：

[1] Leiden Univ, Dept Orthoped Surg, Med Ctr, NL-2300 RC Leiden, Netherlands

[2] Nuffield Orthopaed Ctr, Oxford Sarcoma Serv, Oxford, England

[3] Churchill Hosp, Dept Oncol, Oxford, England

[4] Leiden Univ, Dept Clin Oncol, Med Ctr, NL-2300 RC Leiden, Netherlands

[5] Leiden Univ, Dept Radiol, Med Ctr, NL-2300 RC Leiden, Netherlands

[6] Churchill Hosp, Dept Nucl Med, Oxford, England

[7] Nuffield Orthopaed Ctr, Dept Pathol, Oxford, England

[8] Leiden Univ, Dept Pathol, Med Ctr, NL-2300 RC Leiden, Netherlands

来源：

JOURNAL OF SURGICAL ONCOLOGY | 2013年 / 107卷 / 04期

关键词：

diffuse type giant cell tumor; pigmented villonodular synovitis; giant cell tumor of tendon sheath; nodular tenosynovitis; synovectomy; radiation; isotopes; imatinib; PIGMENTED-VILLONODULAR-SYNOVITIS; COLONY-STIMULATING FACTOR; PARTIAL ARTHROSCOPIC SYNOVECTOMY; SURGICAL-TREATMENT; RHEUMATOID-ARTHRITIS; OSTEOCLAST FORMATION; RADIATION TREATMENT; DIFFUSE; KNEE; ANKLE;

D O I：

10.1002/jso.23220

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Giant cell tumors deriving from synovium are classified into a localized (GCT of tendon sheath; GCT-TS) and diffuse form (diffuse-type GCT, Dt-GCT). We propose a multidisciplinary management based upon a systematic review and authors' opinion. Open excision for GCT-TS and open synovectomy (plus excision) for Dt-GCT is advised to reduce the relatively high recurrence risk. External beam radiotherapy should be considered in severe cases, as Dt-GCT commonly extends extra-articular. J. Surg. Oncol. 2013;107:433445. (c) 2012 Wiley Periodicals, Inc.

引用

页码：433 / 445

页数：13

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