Role of cultivation media in the development of yeast strains for large scale industrial use

被引:158
|
作者
Hahn-Hägerdal, B
Karhumaa, K
Larsson, CU
Gorwa-Grauslund, M
Görgens, J
van Zyl, WH
机构
[1] Lund Univ, LTH, SE-22100 Lund, Sweden
[2] Univ Stellenbosch, Dept Proc Engn, ZA-7602 Stellenbosch, South Africa
[3] Univ Stellenbosch, Dept Microbiol, ZA-7600 Stellenbosch, South Africa
关键词
D O I
10.1186/1475-2859-4-31
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The composition of cultivation media in relation to strain development for industrial application is reviewed. Heterologous protein production and pentose utilization by Saccharomyces cerevisiae are used to illustrate the influence of media composition at different stages of strain construction and strain development. The effects of complex, defined and industrial media are compared. Auxotrophic strains and strain stability are discussed. Media for heterologous protein production and for bulk bio-commodity production are summarized.
引用
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页数:16
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