Assembly of functionalized α-hydroxy carbonyl compounds via combination of N-heterocyclic carbene and Pd catalysts

被引:18
|
作者
He, Jinmei [1 ]
Tang, Shibing [1 ]
Tang, Shouchu [1 ]
Liu, Jian [1 ]
Sun, Yongquan [1 ]
Pan, Xinfu [1 ]
She, Xuegong [1 ,2 ]
机构
[1] Lanzhou Univ, State Key Lab Appl Organ Chem, Dept Chem, Lanzhou 730000, Peoples R China
[2] Lanzhou Univ, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China
关键词
N-heterocyclic carbenes; Benzoin condensations; pi-Allylpalladium; Allylic alkylation; Multicomponent reactions; INTRAMOLECULAR STETTER REACTION; DIELS-ALDER REACTIONS; GAMMA-BUTYROLACTONES; MULTICOMPONENT REACTIONS; NUCLEOPHILIC CARBENES; ALPHA; BETA-UNSATURATED ALDEHYDES; BENZOIN CONDENSATION; EFFICIENT SYNTHESIS; CONJUGATE UMPOLUNG; DIRECT ANNULATIONS;
D O I
10.1016/j.tetlet.2008.11.032
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Functionalized a-hydroxy carbonyl compounds were prepared from various aldehydes and allylic acetates via a multicomponent reaction, which were catalyzed by N-heterocyclic carbene and Pd catalysts in one pot. (c) 2008 Elsevier Ltd. All rights reserved.
引用
收藏
页码:430 / 433
页数:4
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