ANCA antibodies in extrinsic allergic alveolitis

被引:0
|
作者
Sennekamp, J. [1 ]
Schulte, W. [2 ]
Kampe, A. Aufm [1 ]
Ruckert, P. [3 ]
Rolke, M. [3 ]
机构
[1] Malteser Lungen & Allergiezentrum, Bonn, Germany
[2] GFO Kliniken Bonn, Lungenklin, Marienhosp, Bonn, Germany
[3] Gemeinschaftspraxis Drs M Rolke & P Ruckert, Aschaffenburg, Germany
关键词
hypersensitivity pneumonitis; extrinsic allergic alveolitis; autoantibody; IgG antibody; antinuclear antibody; anticytoplasmic antibody; IgG immunoblot; immunofluorescence test;
D O I
10.5414/ALX02154
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Of 29 patients with extrinsic allergic alveolitis, 8 responded to an anti-neurrophil cytoplasmic IgG antibody (ANCA) detected in the serum. The majority of 5 sera were DNA-ANCA, followed by 2 p-ANCA with myeloperoxidase (MPO) specificity and 1 a-ANCA with BPI specificity. To our knowledge, this is the first case-control study of ANCA antibodies in extrinsic allergic alveolitis (hypersensitivity pneumonitis). No symptoms of the known ANCA-associated diseases, especially EGPA (Churg-Strauss syndrome) and GPA (Wegener's disease) were noted in these patients.
引用
收藏
页码:446 / 450
页数:5
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