Synthesis, crystal structures, antimicrobial, antifungal and antituberculosis activities of mixed ligand silver(I) complexes

被引：40

作者：

Altaf, Muhammad ^{[1
]}

Stoeckli-Evans, Helen ^{[2
]}

Cuin, Alexandre ^{[3
]}

Sato, Daisy Nakamura ^{[4
]}

Pavan, Fernando Rogerio ^{[5
]}

Fujimura Leite, Clarice Queico ^{[5
]}

Ahmad, Saeed ^{[6
]}

Bouakka, Mohammed ^{[7
]}

Mimouni, Mostafa ^{[8
]}

Khardli, Fatima Zahra ^{[8
]}

Ben Hadda, Taibi ^{[8
]}

机构：

[1] King Fahd Univ Petr & Minerals, Dept Chem, Dhahran 31261, Saudi Arabia

[2] Univ Neuchatel, Inst Phys, CH-2000 Neuchatel, Switzerland

[3] Univ Fed Juiz de Fora, Dept Quim, BR-36036900 Juiz de Fora, MG, Brazil

[4] Adolfo Lutz Inst, Lab Ribeirao Preto, BR-14085410 Ribeirao Preto, SP, Brazil

[5] UNESP, Fac Ciencias Farmaceut, Dept Ciencias Biol, BR-14800900 Araraquara, SP, Brazil

[6] Univ Engn & Technol, Dept Chem, Lahore, Pakistan

[7] Fac Sci, Biochim Lab, Oujda 6000, Morocco

[8] Fac Sci, Lab Chim Mat, Oujda 60000, Morocco

来源：

POLYHEDRON | 2013年 / 62卷

基金：

瑞士国家科学基金会;

关键词：

Anti-tubercular; Anti-bacterial; Antifungal; Silver(I) complexes; Crystal structure; X-RAY-STRUCTURE; GOLD(I) COMPLEXES; ESCHERICHIA-COLI; HELICAL POLYMER; SOLID-STATE; NANOPARTICLES; ACID; TRIPHENYLPHOSPHINE; PHOSPHINES; IMIDAZOLE;

D O I：

10.1016/j.poly.2013.06.021

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The biological activity of some new mixed silver-phosphane-thio-ligand complexes, with 1:1:2, 1:1:1 and 1:2:1 (Ag:phospine:ligand) compositions, have been examined. Ten compounds were prepared using a series of silver(I) salts [AgX, where X = NO3, ClO4, PF6 and Br], tertiary phosphines and the ligands thiosemicarbazide, 2-(propan-2-ylidene)hydrazinecarbothioamide, and thiazolidine-2-thione. The syntheses were carried out under ambient conditions, and the ten complexes obtained were found to be light stable. All 10 compounds were characterized by elemental analysis, FTIR, and NMR spectroscopy, whereas nine compounds were characterized by X-ray diffraction analysis. The anti-proliferative activities were evaluated by minimum inhibitory concentration (MIC: mu g/mL) in an aqueous suspension system and they all show promising potential activity against selective strains of Gram-positive and Gram-negative bacteria, fungous and Mycrobaterium tuberculosis H(37)Rv. (c) 2013 Elsevier Ltd. All rights reserved.

引用

页码：138 / 147

页数：10

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