Novel Insights into the Pharmacology of Flavonoids

被引：203
作者：
Romano, Barbara [1 ]
Pagano, Ester [1 ]
Montanaro, Vittorino [2 ]
Fortunato, Alfonso L. [1 ]
Milic, Natasa [3 ]
Borrelli, Francesca [1 ]
机构：
[1] Univ Naples Federico II, Dept Urol, I-80131 Naples, Italy
[2] Univ Naples Federico II, Dept Pharm, I-80131 Naples, Italy
[3] Univ Novi Sad, Fac Med, Dept Pharm, Novi Sad 21000, Serbia
来源：
PHYTOTHERAPY RESEARCH | 2013年 / 27卷 / 11期
关键词：
antioxidant; apoptosis; cancer; flavonoids; isoflavonoids; phytoestrogens; quercetin; silybin; WORT HYPERICUM-PERFORATUM; CENTRAL-NERVOUS-SYSTEM; COLON-CANCER CELLS; AIRWAY INFLAMMATION; ANTIOXIDANT FLAVONOIDS; GENE-EXPRESSION; P-GLYCOPROTEIN; QUERCETIN; EXTRACT; RAT;
D O I：
10.1002/ptr.5023
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Flavonoids are widely distributed secondary metabolites and currently consumed in large amounts in the daily diet. In this article, some of the most recent developments in flavonoid - and related polyphenolic compounds - pharmacology are discussed, with particular emphasis on very recent data, most of which are published in Phytotherapy Research, which highlight new aspects in flavonoid anti-inflammatory, antilipidemic, antihyperglycemic, antiviral, hepatoprotective, gastric antiulcer, cardioprotective, neuroprotective, antioxidant and anticancer actions. These updated data confirm the well-established diverse beneficial pharmacological actions and might support the perspective for a therapeutic use. Copyright (c) 2013 John Wiley & Sons, Ltd.
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收藏
页码：1588 / 1596
页数：9
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