Novel Insights into the Pharmacology of Flavonoids

被引：202

作者：

Romano, Barbara ^{[1
]}

Pagano, Ester ^{[1
]}

Montanaro, Vittorino ^{[2
]}

Fortunato, Alfonso L. ^{[1
]}

Milic, Natasa ^{[3
]}

Borrelli, Francesca ^{[1
]}

机构：

[1] Univ Naples Federico II, Dept Urol, I-80131 Naples, Italy

[2] Univ Naples Federico II, Dept Pharm, I-80131 Naples, Italy

[3] Univ Novi Sad, Fac Med, Dept Pharm, Novi Sad 21000, Serbia

来源：

PHYTOTHERAPY RESEARCH | 2013年 / 27卷 / 11期

关键词：

antioxidant; apoptosis; cancer; flavonoids; isoflavonoids; phytoestrogens; quercetin; silybin; WORT HYPERICUM-PERFORATUM; CENTRAL-NERVOUS-SYSTEM; COLON-CANCER CELLS; AIRWAY INFLAMMATION; ANTIOXIDANT FLAVONOIDS; GENE-EXPRESSION; P-GLYCOPROTEIN; QUERCETIN; EXTRACT; RAT;

D O I：

10.1002/ptr.5023

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Flavonoids are widely distributed secondary metabolites and currently consumed in large amounts in the daily diet. In this article, some of the most recent developments in flavonoid - and related polyphenolic compounds - pharmacology are discussed, with particular emphasis on very recent data, most of which are published in Phytotherapy Research, which highlight new aspects in flavonoid anti-inflammatory, antilipidemic, antihyperglycemic, antiviral, hepatoprotective, gastric antiulcer, cardioprotective, neuroprotective, antioxidant and anticancer actions. These updated data confirm the well-established diverse beneficial pharmacological actions and might support the perspective for a therapeutic use. Copyright (c) 2013 John Wiley & Sons, Ltd.

引用

页码：1588 / 1596

页数：9

共 165 条

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