Entheseal Changes in Response to Age, Body Mass Index, and Physical Activity: An Ultrasound Study in Healthy People

被引：51
作者：
Bakirci, Sibel [1 ]
Solmaz, Dilek [1 ]
Stephenson, Wilson [2 ]
Eder, Lihi [3 ,4 ]
Roth, Johannes [5 ,7 ]
Aydin, Sibel Zehra [1 ,6 ]
机构：
[1] Univ Ottawa, Fac Med, Div Rheumatol, Ottawa, ON, Canada
[2] Univ Ottawa, Div Internal Med, Fac Med, Ottawa, ON, Canada
[3] Womens Coll Hosp, Womens Coll Res Inst, Toronto, ON, Canada
[4] Univ Toronto, Dept Med, Toronto, ON, Canada
[5] Childrens Hosp Eastern Ontario, Div Pediat Dermatol & Rheumatol, Ottawa, ON, Canada
[6] Ottawa Hosp Res Inst, Ottawa, ON, Canada
[7] Univ Ottawa, Ottawa, ON, Canada
来源：
JOURNAL OF RHEUMATOLOGY | 2020年 / 47卷 / 07期
关键词：
ENTHESIS; ULTRASOUND; HEALTHY SUBJECTS; ENTHESITIS; SPONDYLOARTHRITIS;
D O I：
10.3899/jrheum.190540
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Objective. We aimed to investigate the prevalence of ultrasonographic (US) lesions in healthy entheses and contributing factors. Methods. US scans were performed on 960 entheses of 80 healthy subjects. Factors contributing to entheseal changes were investigated with regression analysis. Results. Thickening (20.4% of the entheses) and enthesophytes (23.1%) were the most common inflammatory and structural damage lesions, respectively. Age (p < 0.001), male sex (p = 0.003), body mass index (BMI; p = 0.001), and high physical activity (p = 0.007) were independent predictors of enthesitis scores on US. Conclusion. The effects of age, sex, BMI, and physical activity on the entheses need to be considered when differentiating disease from health.
引用
收藏
页码：968 / 972
页数：5
相关论文
共 12 条
  • [1] Greater magnitude of entheseal microdamage and repair in psoriatic arthritis compared with ankylosing spondylitis on ultrasound
    Alhussain, Fatima Arslan
    Gunal, Esen Kasapoglu
    Kurum, Esra
    Bakirci, Sibel
    Ozturk, Ayse Bilge
    McGonagle, Dennis
    Aydin, Sibel Zehra
    [J]. RHEUMATOLOGY, 2019, 58 (02) : 299 - 303
  • [2] Psoriasis patients with nail disease have a greater magnitude of underlying systemic subclinical enthesopathy than those with normal nails
    Ash, Zoe R.
    Tinazzi, Ilaria
    Castillo-Gallego, Concepcion
    Kwok, Chung
    Wilson, Caroline
    Goodfield, Mark
    Gisondi, Paolo
    Tan, Ai Lyn
    Marzo-Ortega, Helena
    Emery, Paul
    Wakefield, Richard J.
    McGonagle, Dennis G.
    Aydin, Sibel Z.
    [J]. ANNALS OF THE RHEUMATIC DISEASES, 2012, 71 (04) : 553 - 556
  • [3] The link between enthesitis and arthritis in psoriatic arthritis: a switch to a vascular phenotype at insertions may play a role in arthritis development
    Aydin, Sibel Z.
    Ash, Zoe R.
    Tinazzi, Ilaria
    Castillo-Gallego, Concepcion
    Kwok, Chung
    Wilson, Caroline
    Goodfield, Mark
    Gisondi, Paolo
    Tan, Ai Lyn
    Marzo-Ortega, Helena
    Emery, Paul
    Wakefield, Richard J.
    McGonagle, Dennis G.
    [J]. ANNALS OF THE RHEUMATIC DISEASES, 2013, 72 (06) : 992 - 995
  • [4] Reliability of a consensus-based ultrasound definition and scoring for enthesitis in spondyloarthritis and psoriatic arthritis: an OMERACT US initiative
    Balint, Peter V.
    Terslev, Lene
    Aegerter, Philippe
    Bruyn, George Arthur Willem
    Chary-Valckenaere, Isabelle
    Gandjbakhch, Frederique
    Iagnocco, Annamaria
    Jousse-Joulin, Sandrine
    Moller, Ingrid
    Naredo, Esperanza
    Schmidt, Wolfgang A.
    Wakefield, Richard J.
    D'Agostino, Maria-Antonietta
    [J]. ANNALS OF THE RHEUMATIC DISEASES, 2018, 77 (12) : 1730 - 1735
  • [5] Eder Lihi, 2019, J Rheumatol Suppl, V95, P51, DOI 10.3899/jrheum.190117
  • [6] Guldberg-Moller J, 2019, CLIN EXP RHEUMATOL, V37, P408
  • [7] Disparity between ultrasound and clinical findings in psoriatic arthritis
    Husic, Rusmir
    Gretler, Judith
    Felber, Anja
    Graninger, Winfried B.
    Duftner, Christina
    Hermann, Josef
    Dejaco, Christian
    [J]. ANNALS OF THE RHEUMATIC DISEASES, 2014, 73 (08) : 1529 - 1536
  • [8] Development and validation of the Spondyloarthritis Research Consortium of Canada (SPARCC) Enthesitis Index
    Maksymowych, W. P.
    Mallon, C.
    Morrow, S.
    Shojania, K.
    Olszynski, W. P.
    Wong, R. L.
    Sampalis, J.
    Conner-Spady, B.
    [J]. ANNALS OF THE RHEUMATIC DISEASES, 2009, 68 (06) : 948 - 953
  • [9] Prevalence of ultrasound synovial inflammatory findings in healthy subjects
    Padovano, Ilaria
    Costantino, Felicie
    Breban, Maxime
    D'Agostino, Maria Antonietta
    [J]. ANNALS OF THE RHEUMATIC DISEASES, 2016, 75 (10) : 1819 - 1823
  • [10] Systematic review of the measurement properties of self-report physical activity questionnaires in healthy adult populations
    Silsbury, Zoe
    Goldsmith, Robert
    Rushton, Alison
    [J]. BMJ OPEN, 2015, 5 (09):
12