Pd-catalysed amination on a soluble polymer support: arylation of anilines with PEG-supported aryl halides

被引：7

作者：

Carvalho, Luisa C. R. ^{[1
]}

Dias Pires, Marina J. ^{[1
]}

Fernandes, Eduarda ^{[2
]}

Marques, M. Manuel B. ^{[1
]}

机构：

[1] Univ Nova Lisboa, Fac Ciencias & Tecnol, Dept Quim, P-2829516 Caparica, Portugal

[2] Univ Porto, Fac Farm, Dept Ciencias Quim, REQUIMTE, P-4050313 Oporto, Portugal

来源：

RSC ADVANCES | 2013年 / 3卷 / 48期

关键词：

SOLID-PHASE SYNTHESIS; POLY(ETHYLENE GLYCOL); POLYETHYLENE-GLYCOL; SOLVENT; SYSTEM; CROSS;

D O I：

10.1039/c3ra45177a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

PEG supported aryl halides were found to serve as substrates for the Pd-catalysed N-arylation of several substituted anilines and alkyl amines under solventless conditions. Moreover, the Pd(2)dba(3)/XPhos catalyst system enabled the coupling reactions to take place smoothly with excellent yields under a low catalyst loading (1 mol% Pd and 3 mol% ligand).

引用

页码：25711 / 25715

页数：5

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