Claudin-1 (CLDN1) as a new therapeutic target in colorectal cancer: Inhibition of cell growth and survival by an anti-CLDN1 monoclonal antibody

被引:1
|
作者
Ayrolles-Torro, Adeline [1 ,2 ,3 ]
Vezzio-Vie, Nadia [1 ,2 ,3 ]
Denis, Vincent [1 ,2 ,3 ]
Boissiere-Michot, Florence [4 ]
Garambois, Veronique [1 ,2 ,3 ]
Busson, Muriel [1 ,2 ,3 ]
Arsa, Imade Ait [1 ,2 ,3 ]
Mollevi, Caroline [4 ]
Pugniere, Martine [1 ,2 ,3 ]
Bibeau, Frederic [4 ]
Martineau, Pierre [1 ,2 ,3 ]
Gongora, Celine [1 ,2 ,3 ]
Del Rio, Maguy [1 ,2 ,3 ]
机构
[1] IRCM, Montpellier, France
[2] INSERM, U896, Montpellier, France
[3] Univ Montpellier I, Montpellier, France
[4] Inst Reg Canc Montpellier, ICM, Montpellier, France
关键词
D O I
10.1158/1535-7163.TARG-13-B245
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
B245
引用
收藏
页数:1
相关论文
共 50 条
  • [31] Claudin-1 is a novel target of miR-375 in non-small-cell lung cancer
    Yoda, Satoshi
    Soejima, Kenzo
    Hamamoto, Junko
    Yasuda, Hiroyuki
    Nakayama, Sohei
    Satomi, Ryosuke
    Terai, Hideki
    Ikemura, Shinnosuke
    Sato, Takashi
    Naoki, Katsuhiko
    Betsuyaku, Tomoko
    LUNG CANCER, 2014, 85 (03) : 366 - 372
  • [32] A monoclonal antibody targeting nonjunctional claudin-1 inhibits fibrosis in patient-derived models by modulating cell plasticity
    Roehlen, Natascha
    Saviano, Antonio
    El Saghire, Houssein
    Crouchet, Emilie
    Nehme, Zeina
    Del Zompo, Fabio
    Juehling, Frank
    Oudot, Marine A.
    Durand, Sarah C.
    Duong, Francois H. T.
    Cherradi, Sara
    Motos, Victor Gonzalez
    Almeida, Nuno
    Ponsolles, Clara
    Heydmann, Laura
    Ostyn, Tessa
    Lallement, Antonin
    Pessaux, Patrick
    Felli, Emanuele
    Cavalli, Andrea
    Sgrignani, Jacopo
    Thumann, Christine
    Koutsopoulos, Olga
    Fuchs, Bryan C.
    Hoshida, Yujin
    Hofmann, Maike
    Vyberg, Mogens
    Viuff, Birgitte Martine
    Galsgaard, Elisabeth D.
    Elson, Greg
    Toso, Alberto
    Meyer, Markus
    Iacone, Roberto
    Schweighoffer, Tamas
    Teixeira, Geoffrey
    Moll, Solange
    De Vito, Claudio
    Roskams, Tania
    Davidson, Irwin
    Heide, Danijela
    Heikenwaelder, Mathias
    Zeisel, Mirjam B.
    Lupberger, Joachim
    Mailly, Laurent
    Schuster, Catherine
    Baumert, Thomas F.
    SCIENCE TRANSLATIONAL MEDICINE, 2022, 14 (676)
  • [33] Expressions of CLDN1 and insulin-like growth factor 2 are associated with poor prognosis in stage N2 non-small cell lung cancer
    ZHANG Zhen-fa
    PEI Bao-xiang
    WANG An-lei
    ZHANG Lian-min
    SUN Bing-sheng
    JIANG Ri-cheng
    WANG Chang-li
    中华医学杂志(英文版), 2013, 126 (19) : 3668 - 3674
  • [34] Circ_0027446 induces CLDN1 expression to promote papillary thyroid cancer cell malignancy by binding to miR-129-5p
    Zhang, Hong
    Zhou, Qi
    Jiang, Jue
    PATHOLOGY RESEARCH AND PRACTICE, 2022, 238
  • [35] Glucocorticoid Receptor (GR/NR3C1) and Notch Signaling Target Transcription Inhibitor HES1 Regulate Colon Epithelia Tight Junction Protein Occludin (OCLN) and Claudin 1 (CLDN1) Cooperatively in Response to Chronic Psychological StressR
    Zheng, Gen
    Hong, Shuangsong
    Zong, Ye
    Creekmore, Amy L.
    Wiley, John W.
    GASTROENTEROLOGY, 2016, 150 (04) : S360 - S360
  • [36] Inhibition of ovarian and endometrial cancer cell proliferation by an anti-ROR1 monoclonal antibody.
    Liu, Dongli
    Kaufmann, Gunnar F.
    Breitmeyer, James B.
    Dickson, Kristie-Ann
    Marsh, Deborah J.
    Ford, Caroline E.
    CANCER RESEARCH, 2021, 81 (13)
  • [37] FIRST-IN-HUMAN PHASE 1 STUDY OF TORL-1-23, A NOVEL CLAUDIN 6 (CLDN6) TARGETED ANTIBODY DRUG CONJUGATE (ADC) IN PATIENTS WITH OVARIAN CANCER
    Konecny, Gottfried
    Hendrickson, Andrea Wahner
    Winterhoff, Boris
    Chander, Cinthiya
    Bilic, Sanela
    Davenport, Simon
    Chung, Adrine
    Miller, Lei-Lani
    Press, Michael
    Letrent, Stephen
    Slamon, Dennis
    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2023, 33 (SUPPL_4) : A67 - A67
  • [38] DDR1 inhibition as a new therapeutic strategy for colorectal cancer
    Sirvent, Audrey
    Lafitte, Marie
    Roche, Serge
    MOLECULAR & CELLULAR ONCOLOGY, 2018, 5 (04):
  • [39] The combination of phosphoinositol with inositol suppresses colorectal cancer growth and metastasis by regulating CLDN23/ RhoA /ROCK1 pathway
    Wang, Haitao
    Wang, Chuhui
    Yang, Ning
    Xu, Zhen
    Han, Yisa
    Liu, Feng
    Li, Xin
    Song, Yang
    JOURNAL OF FUNCTIONAL FOODS, 2023, 111
  • [40] Role of Stromal Fibroblast-Induced WNT7A Associated with Cancer Cell Migration Through the AKT/CLDN1 Signaling Axis in Oral Squamous Cell Carcinoma
    Kayamori, Kou
    Katsube, Ken-ichi
    Hirai, Hideaki
    Harada, Hiroyuki
    Ikeda, Tohru
    LABORATORY INVESTIGATION, 2023, 103 (10)