Efficacy and safety in key patient subgroups of nivolumab (NIVO) alone or combined with ipilimumab (IPI) versus IPI alone in treatment-naive patients with advanced melanoma (MEL) (CheckMate 067)

被引：21

作者：

Larkin, J. ^{[1
]}

Chiarion-Sileni, V. ^{[2
]}

Gonzalez, R. ^{[3
]}

Grob, J. J. ^{[4
]}

Cowey, C. L. ^{[5
]}

Lao, C. D. ^{[6
]}

Wagstaff, J. ^{[7
]}

Hogg, D. ^{[8
]}

Hill, A. ^{[9
]}

Carlino, M. S. ^{[10
,11
]}

Wolter, P. ^{[12
]}

Lebbe, C. ^{[13
]}

Schachter, J. ^{[14
]}

Thomas, L. ^{[15
]}

Hassel, J. C. ^{[16
,17
]}

Lorigan, P. ^{[18
]}

Walker, D. ^{[19
]}

Jiang, J. ^{[20
]}

Hodi, F. S. ^{[21
]}

Wolchok, J. D. ^{[22
,23
,24
]}

机构：

[1] Royal Marsden Hosp, London SW3 6JJ, England

[2] IOV IRCCS Melanoma Oncol Unit, Melanoma Canc Unit, Padua, Italy

[3] Univ Colorado, Ctr Canc, Div Med Oncol, Aurora, CO USA

[4] Aix Marseille Univ, Hop La Timone, APHM, Dept Dermatol & Skin Canc, Marseille, France

[5] Baylor Charles Sammons Canc Ctr, Hematol Med Oncol, Dallas, TX USA

[6] Univ Michigan, Med Oncol, Ann Arbor, MI 48109 USA

[7] South Wales Wales Canc Inst Singleton Hosp, Oncol Clin Trials Unit, Swansea, W Glam, Wales

[8] Univ Toronto, Princess Margaret Hosp, Clin Studies Resource Ctr, Toronto, ON, Canada

[9] Tasman Oncol Res, Dept Hlth, South Gold Coast, Qld, Australia

[10] Melanoma Inst Australia, Sydney, NSW, Australia

[11] Univ Sydney, Med Oncol, Sydney, NSW 2006, Australia

[12] UZ Leuven, Med Oncol, Leuven, Belgium

[13] Univ Paris Diderot, Hop St Luis, Dept Dermatol, Paris, France

[14] Chaim Sheba Med Ctr, Ella Inst Treatment & Res Melanoma & Skin Canc, Inst Oncol, IL-52621 Tel Hashomer, Israel

[15] Ctr Hosp Lyon Sud, Dept Dermatol, F-69310 Pierre Benite, France

[16] Univ Hosp, German Canc Res Ctr, Dept Dermatol, Heidelberg, Germany

[17] Natl Ctr Tumor Dis, Heidelberg, Germany

[18] Christie NHS Fdn Trust, Med Oncol, Manchester, Lancs, England

[19] Bristol Myers Squibb Co, Global Clin Res, Princeton, NJ USA

[20] Bristol Myers Squibb Co, Global Biometr Sci, Hopewell, NJ USA

[21] Harvard Univ, Sch Med, Dana Farber Canc Inst, Dept Med, Boston, MA 02115 USA

[22] Mem Sloan Kettering Canc Ctr, New York, NY 10021 USA

[23] Weill Cornell Med Coll, Melanoma Serv, New York, NY USA

[24] Weill Cornell Med Coll, Immunotherapeut Serv, New York, NY USA

来源：

EUROPEAN JOURNAL OF CANCER | 2015年 / 51卷

关键词：

D O I：

10.1016/S0959-8049(16)31822-6

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

3303

引用

页码：S664 / S665

页数：2