Natural history of type 1 diabetes

被引：168
作者：
Achenbach, P [1 ]
Bonifacio, E [1 ]
Koczwara, K [1 ]
Ziegler, AG [1 ]
机构：
[1] Diabet Res Inst, D-80804 Munich, Germany
来源：
DIABETES | 2005年 / 54卷
关键词：
BETA-CELL AUTOIMMUNITY; ISLET AUTOANTIBODIES; YOUNG DAISY; GERMAN BABYDIAB; GENETIC SUSCEPTIBILITY; IA-2; AUTOANTIBODIES; GENERAL-POPULATION; BIRTH COHORT; RISK-FACTOR; INSULIN;
D O I：
10.2337/diabetes.54.suppl_2.S25
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The natural history of autoinimune type 1 diabetes in children is associated with the appearance of islet autoantibodies early in life, which is influenced by genetic and environmental factors-Once islet autoantibodies have developed, the progression to diabetes in antibody-positive individuals is determined by the age of antibody appearance and by the magnitude of the autoimmunity, in turn related to the age of the subject. Characteristics that describe the magnitude of the autoimmunity can stage progression to type 1 diabetes in islet autoantibody-positive subjects regardless of genetic background or age.
引用
收藏
页码：S25 / S31
页数：7
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