Intensifying the microencapsulation process: Ultrasonic atomization as an innovative approach

被引：86

作者：

Dalmoro, Annalisa ^{[1
,2
]}

Barba, Anna Angela ^{[1
]}

Lamberti, Gaetano ^{[2
]}

d'Amore, Matteo ^{[1
]}

机构：

[1] Univ Salerno, Dipartimento Sci Farmaceut & Biomed, I-84084 Fisciano, SA, Italy

[2] Univ Salerno, Dipartimeno Ingn Ind, I-84084 Fisciano, SA, Italy

来源：

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS | 2012年 / 80卷 / 03期

关键词：

Microencapsulation; Process intensification; Atomization assisted by ultrasonic energy; Microparticles production; POLY(LACTIDE-CO-GLYCOLIDE) MICROSPHERES; SOLVENT EXTRACTION/EVAPORATION; MANUFACTURING PARAMETERS; PROCESS INTENSIFICATION; CONTROLLED-RELEASE; ENCAPSULATION; MICROPARTICLES; THEOPHYLLINE; PROFILES; ATOMIZER;

D O I：

10.1016/j.ejpb.2012.01.006

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

In this review, new approaches to the microencapsulation processes, widely used in the manufacturing of pharmaceutical products, are discussed focusing the attention on the emerging ultrasonic atomization technique. Fundamentals and novel aspects are presented, and advantages of ultrasonic atomization in terms of intensification and low energy requests are emphasized. (C) 2012 Elsevier B.V. All rights reserved.

引用

页码：471 / 477

页数：7

共 60 条

[1] Evaluation of ultrasonic atomization as a new approach to prepare ionically cross-linked chitosan microparticles [J].