Host KIR/HLA-C genotypes determine HIV-mediated changes of the NK cell repertoire and are associated with Vpu sequence variations impacting downmodulation of HLA-C

被引:0
|
作者
Vollmers, S. [1 ]
Lobermeyer, A. [1 ]
Niehrs, A. [1 ]
Fittje, P. [1 ]
Indenbirken, D. [1 ]
Nakel, J. [1 ]
Virdi, S. [1 ]
Brias, S. [1 ,2 ]
Trenkner, T. [1 ]
Sauer, G. [3 ]
Peine, S. [2 ]
Behrens, G. [4 ]
Lehmann, C. [3 ,5 ,6 ]
Meurer, A. [7 ]
Pauli, R. [8 ]
Postel, N. [9 ]
Roider, J. [10 ,11 ]
Scholten, S. [12 ]
Spinner, C. D. [11 ,13 ]
Stephan, C. [14 ]
Wolf, E. [15 ]
Wyen, C. [3 ,16 ]
Richert, L. [17 ]
Norman, P. J. [18 ]
Sauter, J. [19 ]
Schmidt, A. H. [19 ,20 ]
Hoelzemer, A. [1 ,2 ,21 ]
Altfeld, M. [1 ,21 ]
Koener, C. [1 ]
机构
[1] Leibniz Inst Virol, Hamburg, Germany
[2] Univ Med Ctr Hamburg Eppendorf, Hamburg, Germany
[3] Univ Hosp Cologne, Cologne, Germany
[4] Hannover Med Sch, Hannover, NH, Germany
[5] Univ Cologne, Cologne, Germany
[6] German Ctr Infect Res DZIF, Cologne, Germany
[7] Ctr Internal Med & Infectiol, Munich, Germany
[8] MVZ Isartor, Munich, Germany
[9] Prinzmed, Practice Infect Dis, Munich, Germany
[10] Ludwig Maximilians Univ Munchen, Munich, Germany
[11] German Ctr Infect Res DZIF, Munich, Germany
[12] Praxis Hohenstaufenring, Cologne, Germany
[13] Tech Univ Munich, Munich, Germany
[14] Goethe Univ Hosp Frankfurt, Frankfurt, Germany
[15] MUC Res, Munich, Germany
[16] Praxis Ebertpl, Cologne, Germany
[17] Univ Bordeaux, Bordeaux, France
[18] Univ Colorado, Aurora, CO USA
[19] DKMS, Tubingen, Germany
[20] DKMS Life Sci Lab, Dresden, Germany
[21] German Ctr Infect Res DZIF, Hamburg, Germany
关键词
D O I
暂无
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
P 280
引用
收藏
页码:396 / 397
页数:2
相关论文
共 36 条
  • [1] Host KIR/HLA-C Genotypes Determine HIV-Mediated Changes of the NK Cell Repertoire and Are Associated With Vpu Sequence Variations Impacting Downmodulation of HLA-C
    Vollmers, Sarah
    Lobermeyer, Annabelle
    Niehrs, Annika
    Fittje, Pia
    Indenbirken, Daniela
    Nakel, Jacqueline
    Virdi, Sanamjeet
    Brias, Sebastien
    Trenkner, Timo
    Sauer, Gabriel
    Peine, Sven
    Behrens, Georg M. N.
    Lehmann, Clara
    Meurer, Anja
    Pauli, Ramona
    Postel, Nils
    Roider, Julia
    Scholten, Stefan
    Spinner, Christoph D.
    Stephan, Christoph
    Wolf, Eva
    Wyen, Christoph
    Richert, Laura
    Norman, Paul J.
    Sauter, Juergen
    Schmidt, Alexander H.
    Hoelzemer, Angelique
    Altfeld, Marcus
    Koerner, Christian
    FRONTIERS IN IMMUNOLOGY, 2022, 13
  • [2] HLA-C Downmodulation by HIV-1 Vpu
    Barker, Edward
    Evans, David T.
    CELL HOST & MICROBE, 2016, 19 (05) : 570 - 571
  • [3] HIV-1-Mediated Downmodulation of HLA-C Impacts Target Cell Recognition and Antiviral Activity of NK Cells
    Koerner, Christian
    Simoneau, Camille R.
    Schommers, Philipp
    Granoff, Mitchell
    Ziegler, Maja
    Hoelzemer, Angelique
    Lunemann, Sebastian
    Chukwukelu, Janet
    Corleis, Bjorn
    Naranbhai, Vivek
    Kwon, Douglas S.
    Scully, Eileen P.
    Jost, Stephanie
    Kirchhoff, Frank
    Carrington, Mary
    Altfeld, Marcus
    CELL HOST & MICROBE, 2017, 22 (01) : 111 - +
  • [4] Recognition of paternal trophoblast HLA-C by maternal uterine NK cell KIR determines the outcome of pregnancy
    Moffett, A.
    Hiby, S. E.
    Apps, R.
    Sharkey, A. M.
    Farrell, L. E.
    Gardner, L.
    Carrington, M.
    JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 2011, 90 (02) : 137 - 137
  • [5] RECOGNITION OF PATERNAL TROPHOBLAST HLA-C BY MATERNAL UTERINE NK CELL KIR DETERMINES THE OUTCOME OF PREGNANCY
    Moffett, A.
    Hiby, S. E.
    Apps, R.
    Sharkey, A. M.
    Farrell, L. E.
    Gardner, L.
    Carrington, M.
    PLACENTA, 2011, 32 (09) : A122 - A122
  • [6] Evaluation of the presence of the compound KIR: HLA-C genotypes in the virologic outcome of individuals with HIV-1 chronic infection
    Rodriguez-Sainz, C.
    Herraiz, L.
    Hernandez, D. C.
    Valor, L.
    Martinez, I.
    Fernandez-Cruz, E.
    IMMUNOLOGY, 2012, 137 : 516 - 516
  • [7] Blood Donors with HBc Alone: KIR and HLA-C Haplotypes and NK Cell Activity Associated to HBV Clearance and Occult HBV Infection
    Araujo, P. R.
    Latini, F.
    Dodd, R. Y.
    Souza, R.
    Ferreira, O. C.
    Oliveira, J. C.
    Carvalho, F. O.
    Porto, L.
    Diaz, R. S.
    Barreto, J.
    TRANSFUSION, 2012, 52 : 227A - 227A
  • [8] The impact of donor KIR and patient HLA-C genotypes on outcome following HLA-identical sibling hematopoietic stem cell transplantation for myeloid leukemia
    Cook, MA
    Milligan, DW
    Fegan, CD
    Darbyshire, PJ
    Mahendra, P
    Craddock, CF
    Moss, PAH
    Briggs, DC
    BLOOD, 2004, 103 (04) : 1521 - 1526
  • [9] Sequence variations in HCV core-derived epitopes alter binding of KIR2DL3 to HLA-C*03:04 and modulate NK cell function
    Lunemann, Sebastian
    Martrus, Gloria
    Hoelzemer, Angelique
    Chapel, Anais
    Ziegler, Maja
    Koerner, Christian
    Beltran, Wilfredo Garcia
    Carrington, Mary
    Wedemeyer, Heiner
    Altfeld, Marcus
    JOURNAL OF HEPATOLOGY, 2016, 65 (02) : 252 - 258
  • [10] Compatibility of HLA-C KIR ligands & donor recipient KIR genotypes influence outcome following single haplotype matched stem cell transplantation
    De Santis, D
    Witt, C
    Nagler, A
    Brautbar, C
    Christiansen, F
    Bishara, A
    TISSUE ANTIGENS, 2002, 59 : 26 - 26