Rationale Use of Neutrophil-to-lymphocyte ratio for early diagnosis and stratification of COVID-19

被引:28
作者
Zahorec, R. [1 ,2 ]
Hulin, I [3 ]
Zahorec, P. [3 ]
机构
[1] Comenius Univ, St Elizabeths Canc Inst, Dept Anesthesiol & Intens Med, Heydukova 10, SK-81250 Bratislava, Slovakia
[2] Comenius Univ, Med Sch, Heydukova 10, SK-81250 Bratislava, Slovakia
[3] Comenius Univ, Fac Med, Bratislava, Slovakia
来源
BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY | 2020年 / 121卷 / 07期
关键词
neutrophil-to-lymphocyte ratio; corona virus SARS-CoV-2; COVID-19;
D O I
10.4149/BLL_2020_077
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Coronavirus disease is caused by a virus that is the cause of a potentially fatal disease worldwide. Coronavirus is a pathogen that primarily affects the human respiratory system. Coronavirus 2019 (COVID-19) has been named WHO since February 11, 2020. The first cases of COVID-19 were reported in December 2019. In January 2020, COVID-19 infection was identifi ed in hospitalized patients in Wuhan, China. We analyze the role of neutrophil-lymphocyte ratio (NLR) in viral infection with special emphasize on novel corona virus disease-COVID-19. NLR may be used for early detection and may refl ect progression to the more severe illness leading to SARS-CoV-2. In the mini review we investigate the use of NLR as a surrogate marker for diagnosis and stratifi cation of COVID-19. Clinical symptoms such as pneumonia, acute respiratory distress syndrome, acute heart damage have led to death. In some cases, multiple infl ammations have been observed. Treatment with interferon inhalation showed no clinical effect and the condition worsened instead (Tab. 5, Fig. 1, Ref. 18). Text in PDF www.elis.sk
引用
收藏
页码:466 / 470
页数:5
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