Sesquiterpenoids from Nectandra megapotamica (Lauraceae)

被引：6

作者：

Oliveira, Carolina Q. ^{[1
]}

Morandini, Liziane B. ^{[1
]}

Pedroso, Marcelo ^{[1
]}

Neto, Alexandre T. ^{[1
]}

Silva, Ubiratan F. ^{[1
]}

Mostardeiro, Marco A. ^{[1
]}

Dalcol, Ionara I. ^{[1
]}

Morel, Ademir F. ^{[1
]}

机构：

[1] Univ Fed Santa Maria, NPPN, Dept Quim, BR-97105900 Santa Maria, RS, Brazil

来源：

JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY | 2017年 / 28卷 / 01期

关键词：

Nectandra megapotamica; Lauraceae; sesquiterpenoid spectroscopic analysis; antimicrobial activity; OILS;

D O I：

10.5935/0103-5053.20160141

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Five sesquiterpenoid oxides, named nectandrene A, B, C, D, and E, were isolated from the essential oil of the leaves of Nectandra megapotamica. Their structures were elucidated by spectroscopic analysis, and the relative configurations were proposed by their nuclear Overhauser effect (NOESY) spectrum. Three of these isolated compounds displayed significant antimicrobial activity; the compound most active had minimal inhibitory concentration (MIC) values between 3.12 and 25.0 mu g mL(-1) against some tested bacteria, and antifungal activity with MIC values between 12.5 and 25.0 mu g mL(-1).

引用

页码：21 / 29

页数：9

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