Sesquiterpenoids from Nectandra megapotamica (Lauraceae)

被引：6
|
作者：
Oliveira, Carolina Q. [1 ]
Morandini, Liziane B. [1 ]
Pedroso, Marcelo [1 ]
Neto, Alexandre T. [1 ]
Silva, Ubiratan F. [1 ]
Mostardeiro, Marco A. [1 ]
Dalcol, Ionara I. [1 ]
Morel, Ademir F. [1 ]
机构：
[1] Univ Fed Santa Maria, NPPN, Dept Quim, BR-97105900 Santa Maria, RS, Brazil
来源：
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY | 2017年 / 28卷 / 01期
关键词：
Nectandra megapotamica; Lauraceae; sesquiterpenoid spectroscopic analysis; antimicrobial activity; OILS;
D O I：
10.5935/0103-5053.20160141
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Five sesquiterpenoid oxides, named nectandrene A, B, C, D, and E, were isolated from the essential oil of the leaves of Nectandra megapotamica. Their structures were elucidated by spectroscopic analysis, and the relative configurations were proposed by their nuclear Overhauser effect (NOESY) spectrum. Three of these isolated compounds displayed significant antimicrobial activity; the compound most active had minimal inhibitory concentration (MIC) values between 3.12 and 25.0 mu g mL(-1) against some tested bacteria, and antifungal activity with MIC values between 12.5 and 25.0 mu g mL(-1).
引用
收藏
页码：21 / 29
页数：9
相关论文
共 50 条
  • [1] Neolignans from Nectandra megapotamica (Lauraceae) Display in vitro Cytotoxic Activity and Induce Apoptosis in Leukemia Cells
    Ponci, Vitor
    Figueiredo, Carlos R.
    Massaoka, Mariana H.
    de Farias, Camyla F.
    Matsuo, Alisson L.
    Sartorelli, Patricia
    Lago, Joao Henrique G.
    MOLECULES, 2015, 20 (07) : 12757 - 12768
  • [2] CHEMICAL COMPOSITION OF VOLATILE OILS FROM LEAVES OF Nectandra megapotamica SPRENG. (LAURACEAE)
    Romoff, Paulete
    Ferreira, Marcelo J. P.
    Padilla, Ricardo
    Toyama, Daniela O.
    Favero, Oriana A.
    Lago, Joao Henrique G.
    QUIMICA NOVA, 2010, 33 (05): : 1119 - 1121
  • [3] Variability of chemical composition of essential oil from Nectandra megapotamica (Spreng.) Mez (Lauraceae)
    Amaral, Lucio de Paula
    Schindler, Bianca
    Bianchini, Nadia Helena
    Longhi, Solon Jonas
    Arajo de Almeida, Carlos Alberto
    Mallmann, Carlos Augusto
    Heinzmann, Berta Maria
    BOLETIN LATINOAMERICANO Y DEL CARIBE DE PLANTAS MEDICINALES Y AROMATICAS, 2015, 14 (03): : 190 - 205
  • [4] PHENYLPROPANOIDS AND OTHER BIOACTIVE CONSTITUENTS FROM NECTANDRA MEGAPOTAMICA
    Garcez, Fernanda R.
    Garcez, Walmir S.
    Hamerski, Lidilhone
    Miguita, Carlos Henrique
    QUIMICA NOVA, 2009, 32 (02): : 407 - 411
  • [5] Biological properties and chemical composition of essential oil from Nectandra megapotamica (Spreng.) Mez. leaves (Lauraceae)
    Almeida, Karoliny C. R.
    Silva, Bruna B.
    Alves, Cassia C. F.
    Vieira, Tatiana M.
    Crotti, Antonio E. M.
    Souza, Joao M.
    Martins, Carlos H. G.
    Ribeiro, Arthur B.
    Squarisi, Iara S.
    Tavares, Denise C.
    Bernabe, Laura dos S.
    Magalhaes, Lizandra G.
    Miranda, Mayker L. D.
    NATURAL PRODUCT RESEARCH, 2020, 34 (21) : 3149 - 3153
  • [6] Chemical constituents from Nectandra cuspidata Nees - Lauraceae
    Batista, Ana L.
    Yoshida, Nidia C.
    Garcez, Fernanda R.
    Garcez, Walmir S.
    BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2015, 61 : 229 - 231
  • [7] Lignoids Isolated from Nectandra turbacensis (Kunth) Nees (Lauraceae)
    Macias-Villamizar, Victor
    Cuca-Suarez, Luis
    Gonzalez, Florenci V.
    Rodriguez, Santiago
    RECORDS OF NATURAL PRODUCTS, 2016, 10 (05) : 654 - 658
  • [8] Nectandra ovatocaudata, a New Species of Lauraceae from Cajamarca, Peru
    Rohwer, Jens G.
    NOVON, 2012, 22 (02): : 220 - 222
  • [9] 2-Arylbenzofuran Neolignans from the Bark of Nectandra purpurascens (Lauraceae)
    Rios-Motta, Jaime
    Avella, Eliseo
    NATURAL PRODUCT COMMUNICATIONS, 2010, 5 (07) : 1063 - 1066
  • [10] ECOGEOGRAPHICAL DIFFERENTIATION IN NECTANDRA (LAURACEAE), AND ITS HISTORICAL IMPLICATIONS
    ROHWER, JG
    KUBITZKI, K
    BOTANICA ACTA, 1993, 106 (01): : 88 - 99
12345