One-pot oximation-Beckmann rearrangement of ketones and aldehydes to amides of industrial interest: Acetanilide, caprolactam and acetaminophen

被引：40

作者：

Arico, Fabio ^{[2
,3
]}

Quartarone, Giuseppe ^{[1
,2
]}

Rancan, Elia ^{[1
,2
]}

Ronchin, Lucio ^{[1
,2
]}

Tundo, Pietro ^{[2
,3
]}

Vavasori, Andrea ^{[1
,2
]}

机构：

[1] Ca Foscari Univ, Dept Mol Sci & Nanosyst, I-30123 Venice, Italy

[2] Green Chem Grp, I-30123 Venice, Italy

[3] Ca Foscari Univ, Dept Environm Sci Informat & Stat, I-30123 Venice, Italy

来源：

CATALYSIS COMMUNICATIONS | 2014年 / 49卷

关键词：

Amides; Oximation; Beckmann rearrangement; Trifluoroacetic acid; Ketones; TRIFLUOROACETIC-ACID; CYCLOHEXANONE OXIME; ACETOPHENONE OXIMES; EPSILON-CAPROLACTAM; APROTIC-SOLVENT; IONIC LIQUIDS; CONVERSION; CATALYSTS; KETOXIMES; KINETICS;

D O I：

10.1016/j.catcom.2014.02.007

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

High yielding one-pot oximation-Beckmann rearrangement of ketones to amides in ktrifluoroacetic acid has been conducted on several ketones and aldehydes. The substrate reactivity showed to depend on both oximation and Beckmann rearrangement reaction rate. In this synthetic procedure, trifluoroacetic acid acts as solvent, acid catalyst and organocatalyst and can be easily recycled. (C) 2014 Elsevier B.V. All rights reserved.

引用

页码：47 / 51

页数：5

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