Intracranial Mature Teratoma in an Adult Patient: A Case Report

被引:10
作者
Romic, Dominik [1 ]
Raguz, Marina [1 ]
Marcinkovic, Petar [1 ]
Sesar, Patricija [2 ]
Spero, Martina [3 ]
Romic, Zrinka Colak [4 ]
Dlaka, Domagoj [1 ]
Chudy, Darko [1 ]
机构
[1] Univ Hosp Dubrava, Dept Neurosurg, Avenija Gojka Suska 6, HR-10000 Zagreb, Croatia
[2] Univ Hosp Dubrava, Dept Pathol & Cytol, Zagreb, Croatia
[3] Univ Hosp Dubrava, Dept Radiol, Zagreb, Croatia
[4] Univ Hosp Dubrava, Dept Neurol, Zagreb, Croatia
关键词
mature teratoma; adult; intracranial teratoma; GERMINOMA;
D O I
10.1055/s-0039-1685213
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Introduction: Primary intracranial teratoma is a subtype of germ cell tumors, classified into three subtypes. They occur very rarely, with only several reported individual cases in adults. Case Description We present a patient with an intermittent headache in the right frontal region. Magnetic resonance imaging (MRI) revealed a right sided high frontal parasagittal mass that compressed the falx, the right lateral ventricle, as well as the brain parenchyma. Patient underwent surgical treatment. Histopathological analysis described mature teratoma. Four months after the surgical treatment there were no signs of residual intracranial mass or relapse. Discussion Primary intracranial teratoma in adults has a nonspecific clinical presentation. MRI reveals a solitary irregular mass with multilocularity and mixed signals derived from different tissues. The patients age, biochemical markers, and patohistological analysis are necessary to confirm the diagnosis. Conclusion Teratoma treatment strategy still remains controversial. It includes radical resection whenever possible. Since the residual portion of mature teratoma may contain part of immature or malignant tissue, tumor recurrence after surgical removal is possible. Also, new tumor mass could occur at other sites intracranial after the initial one was removed. Thus, although patients usually recover, they should be followed-up for a long period of time.
引用
收藏
页码:E14 / E17
页数:4
相关论文
共 12 条
  • [1] Teratomas in central nervous system: A clinico-morphological study with review of literature
    Agrawal, Meetu
    Uppin, Megha S.
    Patibandla, Mohana R.
    Bhattacharjee, Suchanda
    Panigrahi, Manas K.
    Saradhi, Vijay
    Rani, Jyotsna Y.
    Purohit, A. K.
    Challa, Sundaram
    [J]. NEUROLOGY INDIA, 2010, 58 (06) : 27 - 32
  • [2] Mature cerebellar teratoma in adulthood
    Beschorner, Rudi
    Schittenhelm, Jens
    Bueltmann, Eva
    Ritz, Rainer
    Meyermann, Richard
    Mittelbronn, Michel
    [J]. NEUROPATHOLOGY, 2009, 29 (02) : 176 - 180
  • [3] Mature Intracranial Teratoma
    Dimov, Irena
    Tasic, Desanka
    Stojanovic, Ivana
    Stojanovic, Simonida
    Stojanovic, Nebojsa
    Stefanovic, Ivan
    Dimov, Dragan
    [J]. ACTA FACULTATIS MEDICAE NAISSENSIS, 2013, 30 (02) : 97 - 102
  • [4] Georgiu C, 2016, ROM J MORPHOL EMBRYO, V57, P1389
  • [5] Occurrence of a germinoma 22 years after resection of a mature cerebral teratoma
    Janzarik, Wibke G.
    Mueller, Klaus
    Luebbert, Michael
    Spreer, Joachim
    Trippel, Michael
    Uhlig, Inge
    Weiller, Cornelius
    Rauer, Sebastian
    [J]. JOURNAL OF NEURO-ONCOLOGY, 2008, 88 (02) : 217 - 219
  • [6] Metachronous germinoma after total removal of mature teratoma in the third ventricle: A case report
    Kim, JM
    Cheong, JH
    Yi, HJ
    Bak, KH
    Kim, CH
    Oh, SJ
    [J]. JOURNAL OF KOREAN MEDICAL SCIENCE, 2002, 17 (02) : 287 - 291
  • [7] Central Nervous System Germ Cell Tumors: A Review of the Literature
    Kong, Ziren
    Wang, Yaning
    Dai, Congxin
    Yao, Yong
    Ma, Wenbin
    Wang, Yu
    [J]. JOURNAL OF CHILD NEUROLOGY, 2018, 33 (09) : 610 - 620
  • [8] Treatment and outcomes of primary intracranial teratoma
    Lee, Yun-Ho
    Park, Eun Kyung
    Park, Young Seok
    Shim, Kyu-Won
    Choi, Joong-Uhn
    Kim, Dong-Seok
    [J]. CHILDS NERVOUS SYSTEM, 2009, 25 (12) : 1581 - 1587
  • [9] Imaging characteristics of primary intracranial teratoma
    Liu, Zhenyin
    Lv, Xiaofei
    Wang, Wensheng
    An, Jie
    Duan, Fuhong
    Feng, Xia
    Chen, Xinjian
    Ouyang, Bing
    Li, Songtao
    Singh, Sristi
    Qiu, Shijun
    [J]. ACTA RADIOLOGICA, 2014, 55 (07) : 874 - 881
  • [10] Pecina-Slaus N, 2007, PATHOL ONCOL RES, V13, P370