Marigold Metabolites: Diversity and Separation Methods of Calendula Genus Phytochemicals from 1891 to 2022

被引:12
作者
Olennikov, Daniil N. [1 ]
Kashchenko, Nina I. [1 ]
机构
[1] Russian Acad Sci, Inst Gen & Expt Biol, Siberian Div, Lab Biomed Res, Ulan Ude 670047, Russia
来源
MOLECULES | 2022年 / 27卷 / 23期
关键词
Calendula; marigold; metabolites; separation methods; chromatography; CHROMATOGRAPHY-MASS-SPECTROMETRY; SUPERCRITICAL-FLUID EXTRACTION; OLEANOLIC ACID GLYCOSIDES; IN-VITRO ANTIOXIDANT; OFFICINALIS L; SESQUITERPENE GLYCOSIDES; TRITERPENOID SAPONINS; ESSENTIAL OILS; ANTIINFLAMMATORY ACTIVITY; CAROTENOID COMPOSITION;
D O I
10.3390/molecules27238626
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Marigold (Calendula), an important asteraceous genus, has a history of many centuries of therapeutic use in traditional and officinal medicines all over the world. The scientific study of Calendula metabolites was initiated at the end of the 18th century and has been successfully performed for more than a century. The result is an investigation of five species (i.e., C. officinalis, C. arvensis, C. suffruticosa, C. stellata, and C. tripterocarpa) and the discovery of 656 metabolites (i.e., mono-, sesqui-, di-, and triterpenes, phenols, coumarins, hydroxycinnamates, flavonoids, fatty acids, carbohydrates, etc.), which are discussed in this review. The identified compounds were analyzed by various separation techniques as gas chromatography and liquid chromatography which are summarized here. Thus, the genus Calendula is still a high-demand plant-based medicine and a valuable bioactive agent, and research on it will continue for a long time.
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页数:46
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