High blood pressure (BP) is the strongest risk factor for stroke. It is estimated that almost 50% of strokes may be attributable to hypertension. Both diastolic and isolated systolic hypertension are important predictors of primary or recurrent strokes, and even minor decreases in BP can reduce the risk of stroke. While the primary prevention of stroke through the treatment of hypertension is well established, the issue of lowering BP after a stroke has been uncertain, particularly since this might worsen cerebral perfusion if autoregulation remains chronically damaged or severe carotid artery stenosis is present. Furthermore, there is substantial evidence to support BP lowering for prevention of a first stroke; however, few trials have focused on antihypertensive therapy for recurrent stroke prevention. In fact, currently, BP management in patients with strokes remains problematic, and questions such as the choice of antihypertensive drug and by how much to reduce BP are yet to be resolved. Recently, the American Heart Association and American Stroke Association published updated guidelines for recurrent stroke prevention, and new recommendations on BP management have been included. Our review presents the most recent evidence on the management of hypertension in patients who have had a stroke. Copyright (C) 2012 S. Karger AG, Basel
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Univ Leeds, C NET Res Grp, LIGHT, Fac Med, Leeds LS2 9JT, W Yorkshire, EnglandUniv Leeds, C NET Res Grp, LIGHT, Fac Med, Leeds LS2 9JT, W Yorkshire, England
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McMaster Univ, Populat Hlth Res Inst, Hamilton Hlth Sci, 237 Barton St E, Hamilton, ON L8L 2X2, CanadaMcMaster Univ, Populat Hlth Res Inst, Hamilton Hlth Sci, 237 Barton St E, Hamilton, ON L8L 2X2, Canada
Yusuf, Salim
;
Teo, Koon K.
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McMaster Univ, Populat Hlth Res Inst, Hamilton Hlth Sci, 237 Barton St E, Hamilton, ON L8L 2X2, CanadaMcMaster Univ, Populat Hlth Res Inst, Hamilton Hlth Sci, 237 Barton St E, Hamilton, ON L8L 2X2, Canada
Teo, Koon K.
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Pogue, Janice
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McMaster Univ, Populat Hlth Res Inst, Hamilton Hlth Sci, 237 Barton St E, Hamilton, ON L8L 2X2, CanadaMcMaster Univ, Populat Hlth Res Inst, Hamilton Hlth Sci, 237 Barton St E, Hamilton, ON L8L 2X2, Canada
Pogue, Janice
;
Dyal, Leanne
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McMaster Univ, Populat Hlth Res Inst, Hamilton Hlth Sci, 237 Barton St E, Hamilton, ON L8L 2X2, CanadaMcMaster Univ, Populat Hlth Res Inst, Hamilton Hlth Sci, 237 Barton St E, Hamilton, ON L8L 2X2, Canada
Dyal, Leanne
;
Copland, Ingrid
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McMaster Univ, Populat Hlth Res Inst, Hamilton Hlth Sci, 237 Barton St E, Hamilton, ON L8L 2X2, CanadaMcMaster Univ, Populat Hlth Res Inst, Hamilton Hlth Sci, 237 Barton St E, Hamilton, ON L8L 2X2, Canada
Copland, Ingrid
;
Schumacher, Helmut
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机构:McMaster Univ, Populat Hlth Res Inst, Hamilton Hlth Sci, 237 Barton St E, Hamilton, ON L8L 2X2, Canada
Schumacher, Helmut
;
Ingelheim, Boehringer
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机构:McMaster Univ, Populat Hlth Res Inst, Hamilton Hlth Sci, 237 Barton St E, Hamilton, ON L8L 2X2, Canada
Ingelheim, Boehringer
;
Dagenais, Gilles
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Univ Laval, Heart & Lung Inst, Laval Hosp, Quebec City, PQ, CanadaMcMaster Univ, Populat Hlth Res Inst, Hamilton Hlth Sci, 237 Barton St E, Hamilton, ON L8L 2X2, Canada
Dagenais, Gilles
;
Sleight, Peter
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Univ Oxford, Oxford, EnglandMcMaster Univ, Populat Hlth Res Inst, Hamilton Hlth Sci, 237 Barton St E, Hamilton, ON L8L 2X2, Canada
Sleight, Peter
;
Anderson, Craig
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George Inst Int Hlth, Sydney, NSW, AustraliaMcMaster Univ, Populat Hlth Res Inst, Hamilton Hlth Sci, 237 Barton St E, Hamilton, ON L8L 2X2, Canada
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Univ Leeds, C NET Res Grp, LIGHT, Fac Med, Leeds LS2 9JT, W Yorkshire, EnglandUniv Leeds, C NET Res Grp, LIGHT, Fac Med, Leeds LS2 9JT, W Yorkshire, England
机构:
McMaster Univ, Populat Hlth Res Inst, Hamilton Hlth Sci, 237 Barton St E, Hamilton, ON L8L 2X2, CanadaMcMaster Univ, Populat Hlth Res Inst, Hamilton Hlth Sci, 237 Barton St E, Hamilton, ON L8L 2X2, Canada
Yusuf, Salim
;
Teo, Koon K.
论文数: 0引用数: 0
h-index: 0
机构:
McMaster Univ, Populat Hlth Res Inst, Hamilton Hlth Sci, 237 Barton St E, Hamilton, ON L8L 2X2, CanadaMcMaster Univ, Populat Hlth Res Inst, Hamilton Hlth Sci, 237 Barton St E, Hamilton, ON L8L 2X2, Canada
Teo, Koon K.
;
Pogue, Janice
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机构:
McMaster Univ, Populat Hlth Res Inst, Hamilton Hlth Sci, 237 Barton St E, Hamilton, ON L8L 2X2, CanadaMcMaster Univ, Populat Hlth Res Inst, Hamilton Hlth Sci, 237 Barton St E, Hamilton, ON L8L 2X2, Canada
Pogue, Janice
;
Dyal, Leanne
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h-index: 0
机构:
McMaster Univ, Populat Hlth Res Inst, Hamilton Hlth Sci, 237 Barton St E, Hamilton, ON L8L 2X2, CanadaMcMaster Univ, Populat Hlth Res Inst, Hamilton Hlth Sci, 237 Barton St E, Hamilton, ON L8L 2X2, Canada
Dyal, Leanne
;
Copland, Ingrid
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h-index: 0
机构:
McMaster Univ, Populat Hlth Res Inst, Hamilton Hlth Sci, 237 Barton St E, Hamilton, ON L8L 2X2, CanadaMcMaster Univ, Populat Hlth Res Inst, Hamilton Hlth Sci, 237 Barton St E, Hamilton, ON L8L 2X2, Canada
Copland, Ingrid
;
Schumacher, Helmut
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h-index: 0
机构:McMaster Univ, Populat Hlth Res Inst, Hamilton Hlth Sci, 237 Barton St E, Hamilton, ON L8L 2X2, Canada
Schumacher, Helmut
;
Ingelheim, Boehringer
论文数: 0引用数: 0
h-index: 0
机构:McMaster Univ, Populat Hlth Res Inst, Hamilton Hlth Sci, 237 Barton St E, Hamilton, ON L8L 2X2, Canada
Ingelheim, Boehringer
;
Dagenais, Gilles
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机构:
Univ Laval, Heart & Lung Inst, Laval Hosp, Quebec City, PQ, CanadaMcMaster Univ, Populat Hlth Res Inst, Hamilton Hlth Sci, 237 Barton St E, Hamilton, ON L8L 2X2, Canada
Dagenais, Gilles
;
Sleight, Peter
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h-index: 0
机构:
Univ Oxford, Oxford, EnglandMcMaster Univ, Populat Hlth Res Inst, Hamilton Hlth Sci, 237 Barton St E, Hamilton, ON L8L 2X2, Canada
Sleight, Peter
;
Anderson, Craig
论文数: 0引用数: 0
h-index: 0
机构:
George Inst Int Hlth, Sydney, NSW, AustraliaMcMaster Univ, Populat Hlth Res Inst, Hamilton Hlth Sci, 237 Barton St E, Hamilton, ON L8L 2X2, Canada