Ivacaftor

被引：68

作者：

Davis, Pamela B. ^{[1
]}

Yasothan, Uma ^{[2
]}

Kirkpatrick, Peter

机构：

[1] Case Western Reserve Univ, Sch Med, Cleveland, OH 44106 USA

[2] IMS Hlth, London NW1 6JB, England

来源：

NATURE REVIEWS DRUG DISCOVERY | 2012年 / 11卷 / 05期

关键词：

CYSTIC-FIBROSIS; CFTR POTENTIATOR; MUTATION;

D O I：

10.1038/nrd3723

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

First disease-modifying drug approved in the United States for the treatment of cystic fibrosis in patients with a specific mutation in the gene encoding the cystic fibrosis transmembrane conductance regulator.

引用

页码：349 / 350

页数：2

共 7 条

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