Chemical Reactions Directed Peptide Self-Assembly

被引：17

作者：

Rasale, Dnyaneshwar B. ^{[1
]}

Das, Apurba K. ^{[1
]}

机构：

[1] Indian Inst Technol Indore, Dept Chem, Indore 452017, Madhya Pradesh, India

来源：

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | 2015年 / 16卷 / 05期

关键词：

chemical reaction; peptide; self-assembly; enzyme; native chemical ligation; FREE CLICK CHEMISTRY; IN-SITU GENERATION; CATALYTIC-ACTIVITY; SUPRAMOLECULAR HYDROGEL; RESPONSIVE HYDROGEL; CONVERGENT ROUTES; ACYL RADICALS; BOTTOM-UP; LIGATION; PROTEIN;

D O I：

10.3390/ijms160510797

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Fabrication of self-assembled nanostructures is one of the important aspects in nanoscience and nanotechnology. The study of self-assembled soft materials remains an area of interest due to their potential applications in biomedicine. The versatile properties of soft materials can be tuned using a bottom up approach of small molecules. Peptide based self-assembly has significant impact in biology because of its unique features such as biocompatibility, straight peptide chain and the presence of different side chain functionality. These unique features explore peptides in various self-assembly process. In this review, we briefly introduce chemical reaction-mediated peptide self-assembly. Herein, we have emphasised enzymes, native chemical ligation and photochemical reactions in the exploration of peptide self-assembly.

引用

页码：10797 / 10820

页数：24

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