Ketoacidosis Due to Empagliflozin, a Paradigm Shift: Case Report and Review of Literature

被引：5

作者：

Hernandez-Quiles, Carlos ^{[1
]}

Ramirez-Duque, Nieves ^{[1
]}

Acosta-Delgado, Domingo ^{[2
]}

机构：

[1] Hosp Univ Virgen del Rocio, Internal Med Dept, Seville, Spain

[2] Hosp Univ Virgen del Rocio, Endocrinol Dept, Seville, Spain

来源：

CURRENT DIABETES REVIEWS | 2019年 / 15卷 / 04期

关键词：

Sodium glucose cotransporter 2; SGLT2; inhibitors; empagliflozin; diabetes mellitus; euglycemia; diabetic ketoacidosis; EUGLYCEMIC DIABETIC-KETOACIDOSIS; TYPE-2; CANAGLIFLOZIN;

D O I：

10.2174/1573399814666180726114044

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Introduction: Sodium-glucose cotransporter 2(SGLT2)-inhibitors are new antihyperglycemic agents that have shown a reduction in cardiovascular events in type 2 diabetes mellitus. Recent warnings have been developed about an increased risk of euglycemic and moderate hyperglycemic diabetic ketoacidosis with the use of SGLT2 inhibitors, but its real incidence is not available yet. Case Report: We present a case of DKA with moderate hyperglycemia in a patient treated with metformin and empagliflozin. Conclusion: DKA in patients treated with SGLT2 inhibitors can be presented as euglycemic and moderated hyperglycemia. This special presentation poses a physician's challenge.

引用

页码：259 / 262

页数：4

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