Ketoacidosis Due to Empagliflozin, a Paradigm Shift: Case Report and Review of Literature

被引：4
作者：
Hernandez-Quiles, Carlos [1 ]
Ramirez-Duque, Nieves [1 ]
Acosta-Delgado, Domingo [2 ]
机构：
[1] Hosp Univ Virgen del Rocio, Internal Med Dept, Seville, Spain
[2] Hosp Univ Virgen del Rocio, Endocrinol Dept, Seville, Spain
来源：
CURRENT DIABETES REVIEWS | 2019年 / 15卷 / 04期
关键词：
Sodium glucose cotransporter 2; SGLT2; inhibitors; empagliflozin; diabetes mellitus; euglycemia; diabetic ketoacidosis; EUGLYCEMIC DIABETIC-KETOACIDOSIS; TYPE-2; CANAGLIFLOZIN;
D O I：
10.2174/1573399814666180726114044
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Introduction: Sodium-glucose cotransporter 2(SGLT2)-inhibitors are new antihyperglycemic agents that have shown a reduction in cardiovascular events in type 2 diabetes mellitus. Recent warnings have been developed about an increased risk of euglycemic and moderate hyperglycemic diabetic ketoacidosis with the use of SGLT2 inhibitors, but its real incidence is not available yet. Case Report: We present a case of DKA with moderate hyperglycemia in a patient treated with metformin and empagliflozin. Conclusion: DKA in patients treated with SGLT2 inhibitors can be presented as euglycemic and moderated hyperglycemia. This special presentation poses a physician's challenge.
引用
收藏
页码：259 / 262
页数：4
相关论文
共 50 条
  • [1] Canagliflozin-Induced Diabetic Ketoacidosis: Case Report and Review of the Literature
    Turner, Jessica
    Begum, Tahmina
    Smalligan, Roger D.
    JOURNAL OF INVESTIGATIVE MEDICINE HIGH IMPACT CASE REPORTS, 2016, 4 (03):
  • [2] Severe euglycemic diabetic ketoacidosis of multifactorial etiology in a type 2 diabetic patient treated with empagliflozin: case report and literature review
    Sampani, Erasmia
    Sarafidis, Pantelis
    Dimitriadis, Chrysostomos
    Kasimatis, Efstratios
    Daikidou, Dimitra
    Bantis, Konstantinos
    Papanikolaou, Alexios
    Papagianni, Aikaterini
    BMC NEPHROLOGY, 2020, 21 (01)
  • [3] Risk of Euglycemic Diabetic Ketoacidosis Due to Low-carbohydrate Diet While Taking Empagliflozin: a Case Report
    Yamamoto, Mariko
    Ide, Naohito
    Kitajima, Shinzo
    Obayashi, Masakazu
    Asada, Kei
    Matsushima, Satoru
    Ito, Masaharu
    YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 2019, 139 (11): : 1479 - 1483
  • [4] Empagliflozin induced euglycemic diabetic ketoacidosis. A case reports
    Altowayan, Waleed M.
    ANNALS OF MEDICINE AND SURGERY, 2022, 84
  • [5] A Case of Euglycemic Diabetic Ketoacidosis due to Empagliflozin Use in a Patient with Type 1 Diabetes Mellitus
    Bilgin, Satilmis
    Duman, Tuba Taslamacioglu
    Kurtkulagi, Ozge
    Yilmaz, Feyza
    Aktas, Gulali
    JCPSP-JOURNAL OF THE COLLEGE OF PHYSICIANS AND SURGEONS PAKISTAN, 2022, 32 (07): : 928 - 930
  • [6] Post hysterectomy ketoacidosis due to empagliflozin
    Gonzalez Leon, Claudia
    Macia Ubierna, Jorge
    Mendieta Zeron, Hugo
    REVISTA PERUANA DE GINECOLOGIA Y OBSTETRICIA, 2020, 66 (01): : 73 - 77
  • [7] Agenesis of the dorsal pancreas presenting with diabetic ketoacidosis - a case report and literature review
    Yang, Tian
    Yang, Xudan
    Wang, Luping
    Mo, Jun
    BMC ENDOCRINE DISORDERS, 2019, 19 (01)
  • [8] Severe euglycemic diabetic ketoacidosis of multifactorial etiology in a type 2 diabetic patient treated with empagliflozin: case report and literature review
    Erasmia Sampani
    Pantelis Sarafidis
    Chrysostomos Dimitriadis
    Efstratios Kasimatis
    Dimitra Daikidou
    Konstantinos Bantis
    Alexios Papanikolaou
    Aikaterini Papagianni
    BMC Nephrology, 21
  • [9] Euglycemic diabetic ketoacidosis associated with sodium-glucose cotransporter-2 inhibitor use: a case report and review of the literature
    Diaz-Ramos, Alexis
    Eilbert, Wesley
    Marquez, Diego
    INTERNATIONAL JOURNAL OF EMERGENCY MEDICINE, 2019, 12 (01)
  • [10] Agenesis of the dorsal pancreas presenting with diabetic ketoacidosis – a case report and literature review
    Tian Yang
    Xudan Yang
    Luping Wang
    Jun Mo
    BMC Endocrine Disorders, 19
12345