Polyacrylic acid@zeolitic imidazolate framework-8 nanoparticles with ultrahigh drug loading capability for pH-sensitive drug release

被引：235
作者：
Ren, Hong [1 ]
Zhang, Lingyu [1 ]
An, Jiping [2 ]
Wang, Tingting [3 ]
Li, Lu [1 ]
Si, Xiaoyan [1 ]
He, Liu [1 ]
Wu, Xiaotong [1 ]
Wang, Chungang [1 ]
Su, Zhongmin [1 ]
机构：
[1] NE Normal Univ, Fac Chem, Changchun 130024, Peoples R China
[2] Jilin Univ, Hosp Stomatol, Changchun 130021, Peoples R China
[3] Changchun Univ Sci & Technol, Sch Chem & Environm Engn, Changchun 130022, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 08期
基金：
中国国家自然科学基金;
关键词：
CORE-SHELL; DELIVERY; MICROSPHERES; FABRICATION; NANOSPHERES; ZIF-8;
D O I：
10.1039/c3cc47666a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The polyacrylic acid@zeolitic imidazolate framework-8 (PAA@ZIF-8) nanoparticles (NPs) were first fabricated using a facile and simple route. It is worthwhile noting that the as-fabricated PAA@ZIF-8 NPs possessed ultrahigh doxorubicin (DOX) loading capability (1.9 g DOX g(-1) NPs), which were employed as pH-dependent drug delivery vehicles.
引用
收藏
页码：1000 / 1002
页数：3
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