ATHEROGENIC DYSLIPIDEMIA AND INFLAMMATION IN HIRSUTISM: NON-HDL CHOLESTEROL AND NON-HDL TO HDL RATIO ARE HIGHER IN WOMEN WITH HIRSUTISM

被引：0

作者：

Deniz, Avci ^{[1
]}

Atil, Avci ^{[2
]}

Cetinkaya, Ali ^{[1
]}

Selahattin, Erdem ^{[1
]}

Hatice, Karakose Dogan ^{[3
]}

Ertas, Ragip ^{[2
]}

Kemal, Ozyurt ^{[2
]}

机构：

[1] Kayseri Training & Res Hosp, Internal Med, Kayseri, Turkey

[2] Kayseri Training & Res Hosp, Dept Dermatol & Venereol, Kayseri, Turkey

[3] Kayseri Training & Res Hosp, Endocrinol & Metab, Kayseri, Turkey

来源：

ACTA MEDICA MEDITERRANEA | 2019年 / 35卷 / 02期

关键词：

Atherogenic; Non-HDL; hirsutism; Non-HDL/HDLHDL Ratio; inflammation; Uric acid; URIC-ACID; CARDIOVASCULAR-DISEASE; METABOLIC SYNDROME; LDL-CHOLESTEROL; SEX-HORMONES; TESTOSTERONE; RISK; MEN;

D O I：

10.19193/0393-6384_2019_2_171

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Aim: The purpose of this research is to investigate the situation of atherogenic lipids in women with hirsutism and to compare the atherogenic lipid parameters with the sex hormones Material and methods: The non-HDL levels and Non-HDL to HDL were compared between 66 kontrols and 134 women with hirsutism. Patients' hormonal parameters were compared with Non-HDL values and Non-HDL to HDL ratios. Results: Non-HDL-c level was 109.7 +/- 29.2 in the control group and 129.2 +/- 36.1 in hirsutism group. (p<0.001). Mean Non-HDL/HDL level of the control group was 2.17 +/- 0.84. this value was 2.64 +/- 0.96 in the hirsutism group (p<0.001). There was a statistically significant correlation (r=0.248, p=0.013) between the uric acid and insulin in patients group. Conclusion: There was statically significant elevations of serum atherogenic lipids in women with hirsutism.

引用

页码：1109 / 1114

页数：6

共 29 条

[21]

Rocha EPAA, 2018, HORM RES PAEDIAT, P1

[22] The role of testosterone in type 2 diabetes and metabolic syndrome in men [J].

Saad, Farid .

ARQUIVOS BRASILEIROS DE ENDOCRINOLOGIA E METABOLOGIA, 2009, 53 (08) :901-907

[23] Adverse effects of the classic antioxidant uric acid in adipocytes: NADPH oxidase-mediated oxidative/nitrosative stress [J].

Sautin, Yuri Y. ;

Nakagawa, Takahiko ;

Zharikov, Sergey ;

Johnson, Richard J. .

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2007, 293 (02) :C584-C596

[24] LIPID PROFILES IN WOMEN WITH HIRSUTISM AND POLYCYSTIC OVARIES [J].

SENOZ, S ;

OZAKSIT, G ;

TURHAN, NO ;

GULEKLI, B ;

GOKMEN, O .

GYNECOLOGICAL ENDOCRINOLOGY, 1994, 8 (01) :33-37

[25] Discordance analysis and the Gordian Knot of LDL and non-HDL cholesterol versus apoB [J].

Sniderman, Allan D. ;

Lamarche, Benoit ;

Contois, John H. ;

de Graaf, Jacqueline .

CURRENT OPINION IN LIPIDOLOGY, 2014, 25 (06) :461-467

[26]

Stanworth RD, 2009, FRONT HORM RES, V37, P74, DOI 10.1159/000176046

[27] Lowering Uric Acid With Allopurinol Improves Insulin Resistance and Systemic Inflammation in Asymptomatic Hyperuricemia [J].

Takir, Mumtaz ;

Kostek, Osman ;

Ozkok, Abdullah ;

Elcioglu, Omer Celal ;

Bakan, Ali ;

Erek, Aybala ;

Mutlu, Hasan Huseyin ;

Telci, Ozge ;

Semerci, Aysun ;

Odabas, Ali Riza ;

Afsar, Baris ;

Smits, Gerard ;

ALanaspa, Miguel ;

Sharma, Shailendra ;

Johnson, Richard J. ;

Kanbay, Mehmet .

JOURNAL OF INVESTIGATIVE MEDICINE, 2015, 63 (08) :924-929

[28] The Dark Side of Testosterone Deficiency: II. Type 2 Diabetes and Insulin Resistance [J].

Traish, Abdulmaged M. ;

Saad, Farid ;

Guay, Andre .

JOURNAL OF ANDROLOGY, 2009, 30 (01) :23-32

[29] High uric acid directly inhibits insulin signalling and induces insulin resistance [J].

Zhu, Yuzhang ;

Hu, Yaqiu ;

Huang, Tianliang ;

Zhang, Yongneng ;

Li, Zhi ;

Luo, Chaohuan ;

Luo, Yinfeng ;

Yuan, Huier ;

Hisatome, Ichiro ;

Yamamoto, Tetsuya ;

Cheng, Jidong .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2014, 447 (04) :707-714

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