Three-dimensional quantitative force maps in liquid with 10 piconewton, angstrom and sub-minute resolutions

被引：111

作者：

Herruzo, Elena T. ^{[1
]}

Asakawa, Hitoshi ^{[2
]}

Fukuma, Takeshi ^{[2
,3
]}

Garcia, Ricardo ^{[1
]}

机构：

[1] Inst Ciencia Mat Madrid CSIC, Madrid 28049, Spain

[2] Kanazawa Univ, BioAFM Frontier Res Ctr, Kanazawa, Ishikawa 9201192, Japan

[3] Kanazawa Univ, Div Elect & Comp Engn, Kanazawa, Ishikawa 9201192, Japan

来源：

NANOSCALE | 2013年 / 5卷 / 07期

基金：

日本科学技术振兴机构;

关键词：

DEFLECTION SENSOR; MICROSCOPY; ENERGY; WATER;

D O I：

10.1039/c2nr33051b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We develop a bimodal force microscopy method to map the three-dimensional force fields and their time-evolution on a variety of solid-water interfaces. The force maps show an oscillatory decaying force perpendicular to the solid surface with a 0.3 nm periodicity. The technique enables the three-dimensional imaging and mapping of the hydration layers and forces on mica and protein GroEL surfaces with 10 piconewton, 2 angstrom and 40 second (whole volume) resolutions. We record the existence and evolution of nanoscale perturbations involving thousands of water molecules of the protein-liquid interface. Those instabilities are not found in stiff and atomically flat interfaces.

引用

页码：2678 / 2685

页数：8

共 42 条

[1]

Albers BJ, 2009, NAT NANOTECHNOL, V4, P307, DOI [10.1038/NNANO.2009.57, 10.1038/nnano.2009.57]

[2] Structure and Orientation of Interfacial Water Determine Atomic Force Microscopy Results: Insights from Molecular Dynamics Simulations [J].