Transamidation of primary amides with amines catalyzed by zirconocene dichloride

被引：83

作者：

Atkinson, Benjamin N. ^{[1
]}

Chhatwal, A. Rosie ^{[1
]}

Lomax, Helen V. ^{[1
]}

Walton, James W. ^{[1
]}

Williams, Jonathan M. J. ^{[1
]}

机构：

[1] Univ Bath, Bath BA2 7AY, Avon, England

来源：

CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 95期

基金：

英国工程与自然科学研究理事会;

关键词：

CARBOXYLIC-ACIDS; BOND FORMATION; N-FORMYLATION; PRIMARY CARBOXAMIDES; ALCOHOLS; ACTIVATION; CONVERSION;

D O I：

10.1039/c2cc37427g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Zirconocene dichloride (Cp2ZrCl2) has been shown to be an effective catalyst for the transamidation of primary amides with amines in cyclohexane at 80 degrees C in 5-24 hours. For favourable substrates, the reaction can be performed at temperatures as low as 30 degrees C.

引用

收藏

页码：11626 / 11628

页数：3

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