Infantile Hemangiomas An Update

被引:27
作者
Kwon, Eun-Kyung Mary [1 ]
Seefeldt, Marcia [2 ]
Drolet, Beth A. [2 ]
机构
[1] Med Coll Wisconsin, Dept Dermatol, TBRC, Milwaukee, WI 53226 USA
[2] Med Coll Wisconsin, Dept Dermatol & Pediat, TBRC, Milwaukee, WI 53226 USA
关键词
INTRALESIONAL CORTICOSTEROID-THERAPY; DIFFUSE NEONATAL HEMANGIOMATOSIS; LIFE-THREATENING HEMANGIOMAS; RANDOMIZED CONTROLLED-TRIAL; DYE-LASER TREATMENT; PHACE SYNDROME; PROPRANOLOL THERAPY; HEPATIC HEMANGIOMA; ENDOTHELIAL-CELLS; ORAL PROPRANOLOL;
D O I
10.1007/s40257-013-0008-x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Infantile hemangioma (IH) is a common vascular tumor of infancy. Although benign, infants with IH can experience complications including ulceration, visual and airway impairment, and residual scarring and disfigurement. It is often challenging for clinicians to predict which tumors are in need of systemic treatment. However, data from various demographic and other studies have revealed further insights into this tumor. This article reviews the identification, evaluation, and management of high-risk IHs, including the indications for treatment and the use of systemic treatments such as corticosteroids, beta-blockers, and vincristine.
引用
收藏
页码:111 / 123
页数:13
相关论文
共 141 条
[61]  
Holland KE, 2010, ARCH DERMATOL, V146, P775, DOI 10.1001/archdermatol.2010.158
[62]   Risk of Hepatic Hemangiomas in Infants With Large Hemangiomas [J].
Horii, Kimberly A. ;
Drolet, Beth A. ;
Baselga, Eulalia ;
Frieden, Ilona J. ;
Metry, Denise W. ;
Morel, Kimberly D. ;
Newell, Brandon D. ;
Nopper, Amy J. ;
Garzon, Maria C. .
ARCHIVES OF DERMATOLOGY, 2010, 146 (02) :201-203
[63]  
HOSKINS HD, 1985, ARCH OPHTHALMOL-CHIC, V103, P1163
[64]   Brief report: Severe hypothyroidism caused by type 3 iodothyronine deiodinase in infantile hemangiomas. [J].
Huang, SA ;
Tu, HM ;
Harney, JW ;
Venihaki, M ;
Butte, AJ ;
Kozakewich, HPW ;
Fishman, SJ ;
Larsen, PR .
NEW ENGLAND JOURNAL OF MEDICINE, 2000, 343 (03) :185-189
[65]   LUMBAR: Association between Cutaneous Infantile Hemangiomas of the Lower Body and Regional Congenital Anomalies [J].
Iacobas, Ionela ;
Burrows, Patricia E. ;
Frieden, Ilona J. ;
Liang, Marilyn G. ;
Mulliken, John B. ;
Mancini, Anthony J. ;
Kramer, Daniela ;
Paller, Amy S. ;
Silverman, Robert ;
Wagner, Annette M. ;
Metry, Denise W. .
JOURNAL OF PEDIATRICS, 2010, 157 (05) :795-U140
[66]   Unusual Case of Hypothyroidism in an Infant With Hepatic Hemangioma [J].
Imteyaz, Hejab ;
Karnsakul, Wikrom ;
Levine, Michael A. ;
Burrows, Patricia E. ;
Benson, Jane ;
Hsu, Stephanie ;
Schwarz, Kathleen B. .
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 2012, 54 (05) :692-695
[67]   A placental chorionic villous mesenchymal core cellular origin for infantile haemangioma [J].
Itinteang, Tinte ;
Tan, Swee T. ;
Guthrie, Siobhan ;
Tan, Cherise E. S. ;
McIntyre, Ben C. ;
Brasch, Helen D. ;
Day, Darren J. .
JOURNAL OF CLINICAL PATHOLOGY, 2011, 64 (10) :870-874
[68]   Expression of components of the renin-angiotensin system in proliferating infantile haemangioma may account for the propranolol-induced accelerated involution [J].
Itinteang, Tinte ;
Brasch, Helen D. ;
Tan, Swee T. ;
Day, Darren J. .
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY, 2011, 64 (06) :759-765
[69]   Treatment with interferon-α-2b in children with life-threatening hemangiomas [J].
Jimenez-Hernandez, Elva ;
Duenas-Gonzalez, Maria Teresa ;
Quintero-Curiel, Jose Luis ;
Velasquez-Ortega, Jose ;
Magana-Perez, Jose A. ;
Berges-Garcia, Adolfina ;
Arellano-Galindo, Jose .
DERMATOLOGIC SURGERY, 2008, 34 (05) :640-647
[70]   Suppressed NFAT-dependent VEGFR1 expression and constitutive VEGFR2 signaling in infantile hemangioma [J].
Jinnin, Masatoshi ;
Medici, Damian ;
Park, Lucy ;
Limaye, Nisha ;
Liu, Yanqiu ;
Boscolo, Elisa ;
Bischoff, Joyce ;
Vikkula, Miikka ;
Boye, Eileen ;
Olsen, Bjorn R. .
NATURE MEDICINE, 2008, 14 (11) :1236-1246