Infantile Hemangiomas An Update

被引:27
作者
Kwon, Eun-Kyung Mary [1 ]
Seefeldt, Marcia [2 ]
Drolet, Beth A. [2 ]
机构
[1] Med Coll Wisconsin, Dept Dermatol, TBRC, Milwaukee, WI 53226 USA
[2] Med Coll Wisconsin, Dept Dermatol & Pediat, TBRC, Milwaukee, WI 53226 USA
关键词
INTRALESIONAL CORTICOSTEROID-THERAPY; DIFFUSE NEONATAL HEMANGIOMATOSIS; LIFE-THREATENING HEMANGIOMAS; RANDOMIZED CONTROLLED-TRIAL; DYE-LASER TREATMENT; PHACE SYNDROME; PROPRANOLOL THERAPY; HEPATIC HEMANGIOMA; ENDOTHELIAL-CELLS; ORAL PROPRANOLOL;
D O I
10.1007/s40257-013-0008-x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Infantile hemangioma (IH) is a common vascular tumor of infancy. Although benign, infants with IH can experience complications including ulceration, visual and airway impairment, and residual scarring and disfigurement. It is often challenging for clinicians to predict which tumors are in need of systemic treatment. However, data from various demographic and other studies have revealed further insights into this tumor. This article reviews the identification, evaluation, and management of high-risk IHs, including the indications for treatment and the use of systemic treatments such as corticosteroids, beta-blockers, and vincristine.
引用
收藏
页码:111 / 123
页数:13
相关论文
共 141 条
[41]   Vincristine as a treatment for a large haemangioma threatening vital functions [J].
Fawcett, SL ;
Grant, I ;
Hall, PN ;
Kelsall, AWR ;
Nicholson, JC .
BRITISH JOURNAL OF PLASTIC SURGERY, 2004, 57 (02) :168-171
[42]   SUCCESSFUL TREATMENT OF JUVENILE HEMANGIOMAS WITH PREDNISONE [J].
FOST, NC ;
ESTERLY, NB .
JOURNAL OF PEDIATRICS, 1968, 72 (03) :351-+
[43]   PHACE syndrome - The association of posterior fossa brain malformations, hemangiomas, arterial anomalies, coarctation of the aorta and cardiac defects, and eye abnormalities [J].
Frieden, IJ ;
Reese, V ;
Cohen, D .
ARCHIVES OF DERMATOLOGY, 1996, 132 (03) :307-311
[44]  
Frieden Ilona J, 2005, Pediatr Dermatol, V22, P383, DOI 10.1111/j.1525-1470.2005.00102.x
[45]   Propranolol as First-line Treatment of Head and Neck Hemangiomas [J].
Fuchsmann, Carine ;
Quintal, Marie-Claude ;
Giguere, Chantal ;
Ayari-Khalfallah, Sonia ;
Guibaud, Laurent ;
Powell, Julie ;
McCone, Catherine ;
Froehlich, Patrick .
ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 2011, 137 (05) :471-478
[46]  
Garzon MC, 2008, DERMATOLOGY, P1574
[47]   Adverse effects of systemic glucocorticosteroid therapy in infants with hemangiomas [J].
George, ME ;
Sharma, V ;
Jacobson, J ;
Simon, S ;
Nopper, AJ .
ARCHIVES OF DERMATOLOGY, 2004, 140 (08) :963-969
[48]   ORAL PROPRANOLOL TREATMENT IN INFANTS AND CHILDREN [J].
GILLETTE, P ;
GARSON, A ;
ETEROVIC, E ;
NECHES, W ;
MULLINS, C ;
MCNAMARA, DG .
JOURNAL OF PEDIATRICS, 1978, 92 (01) :141-144
[49]   PELVIS syndrome [J].
Girard, Celine ;
Bigorre, Michele ;
Guillot, Bernard ;
Bessis, Didier .
ARCHIVES OF DERMATOLOGY, 2006, 142 (07) :884-888
[50]   Rapamycin Suppresses Self-Renewal and Vasculogenic Potential of Stem Cells Isolated from Infantile Hemangioma [J].
Greenberger, Shoshana ;
Yuan, Siming ;
Walsh, Logan A. ;
Boscolo, Elisa ;
Kang, Kyu-Tae ;
Matthews, Benjamin ;
Mulliken, John B. ;
Bischoff, Joyce .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2011, 131 (12) :2467-2476