Pathogenesis and therapy of cutaneous lymphomas - Progress or impasse?

被引：7

作者：

Dummer, R ^{[1
]}

Cozzio, A ^{[1
]}

Urosevic, M ^{[1
]}

机构：

[1] Univ Zurich Hosp, Dept Dermatol, CH-8091 Zurich, Switzerland

来源：

EXPERIMENTAL DERMATOLOGY | 2006年 / 15卷 / 05期

关键词：

CD4(+)CD56(+) hematodermic neoplasm; lymphomagenesis; non-Hodgkin lymphomas; plasmacytoid dendritic cells; primary cutaneous lymphomas;

D O I：

10.1111/j.0906-6705.2006.00419.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

The cutaneous environment hosts a number of hematopoietic neoplasms that are dominated by primary cutaneous (PC) T-cell lymphomas. Recent progress in molecular biology and immunology has provided tools to investigate the pathogenesis and the biology of these neoplasms. This review highlights newest findings concerning the immune biology of CD4(+)CD56(+) hematodermic neoplasms, and PC T-cell and B-cell lymphomas, speculating how these can be translated into more sophisticated, biology-based treatment approaches in the near future.

引用

页码：392 / 400

页数：9

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