Development of drug delivery systems based on nanostructured porous silicon loaded with the anti-tumoral drug emodin adsorbed on silver nanoparticles

被引：1
作者：
Hernandez, Margarita [1 ]
Recio, Gonzalo [2 ]
Sevilla, Paz [1 ,3 ]
Torres-Costa, Vicente [2 ]
Garcia-Ramos, Jose V. [1 ]
Domingo, Concepcion [1 ]
Martin-Palma, Raul J. [2 ]
机构：
[1] CSIC, Inst Estruct Mat, C Serrano 121, Madrid 28006, Spain
[2] Univ Autonoma Madrid, Dept Fis Aplicada, E-28049 Madrid, Spain
[3] Univ Complutense Madrid, Fac Farmac, Dept Quim Fis, Madrid 28040, Spain
来源：
NANOSTRUCTURED THIN FILMS V | 2012年 / 8465卷
关键词：
Nanostructured porous silicon; emodin; Raman; drug delivery;
D O I：
10.1117/12.931117
中图分类号：
TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
A study of the fluorescence and Raman spectra of a new and complex drug delivery system formed by emodin adsorbed on silver nanoparticles embedded into a matrix of porous silicon is here reported. Several experimental methods of inclusion of the drug-silver set inside the pores, without previous functionalization of porous silicon, have been tested in order to optimize the conditions for the fluorescence detection of emodin. In this sense, we have also added bovine serum albumin to the system, finding that the presence of the protein enhances the fluores-cence signal from emodin.
引用
收藏
页数：5
相关论文
共 50 条
  • [21] Hybrid nanofibers based on poly-caprolactone/gelatin/hydroxyapatite nanoparticles-loaded Doxycycline: Effective anti-tumoral and antibacterial activity
    Ramirez-Agudelo, Ricardo
    Scheuermann, Karina
    Gala-Garcia, Alfonso
    Monteiro, Ana Paula F.
    Pinzon-Garcia, Ana Delia
    Cortes, Maria E.
    Sinisterra, Ruben D.
    MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2018, 83 : 25 - 34
  • [22] Metallothermic Reduction of Silica Nanoparticles to Porous Silicon for Drug Delivery Using New and Existing Reductants
    Lai, Yiqi
    Thompson, Jonathan R.
    Dasog, Mita
    CHEMISTRY-A EUROPEAN JOURNAL, 2018, 24 (31) : 7913 - 7920
  • [23] Synthesis of methylprednisolone loaded ibuprofen modified inulin based nanoparticles and their application for drug delivery
    Zhang, Luzhong
    Li, Yue
    Wang, Caiping
    Li, Guicai
    Zhao, Yahong
    Yang, Yumin
    MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2014, 42 : 111 - 115
  • [24] Injectable drug loaded gelatin based scaffolds as minimally invasive approach for drug delivery system: CNC/PAMAM nanoparticles
    Goodarzi, Kasra
    Shariatzadeh, Farinaz Jonidi
    Solouk, Atefeh
    Akbari, Somaye
    Mirzadeh, Hamid
    EUROPEAN POLYMER JOURNAL, 2020, 139
  • [25] Development of Drug Delivery Systems Based on Layered Hydroxides for Nanomedicine
    Barahuie, Farahnaz
    Hussein, Mohd Zobir
    Fakurazi, Sharida
    Zainal, Zulkarnain
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2014, 15 (05) : 7750 - 7786
  • [26] BioMOF-Based Anti-Cancer Drug Delivery Systems
    Elmehrath, Sandy
    Nguyen, Ha L.
    Karam, Sherif M.
    Amin, Amr
    Greish, Yaser E.
    NANOMATERIALS, 2023, 13 (05)
  • [27] Hybrid porous silicon/green synthetized Ag microparticles as potential carries for Ag nanoparticles and drug delivery
    Hernandez-Montelongo, Jacobo
    Fernandez-Fierro, Cristian
    Benito-Gomez, Noelia
    Romero-Saez, Manuel
    Parodi, Jorge
    Carmona, Erico R.
    Recio-Sanchez, Gonzalo
    MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2020, 116
  • [28] Oxidized Porous Silicon Nanoparticles Covalent-Bonded with Levofloxacin in Hydrogel Polymer as a Drug Delivery System
    Kim, Hajin
    Sohn, Honglae
    JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, 2020, 20 (08) : 4619 - 4623
  • [29] Chitosan-based nanoparticles as drug delivery systems for doxorubicin: Optimization and modelling
    Soares, Paula I. P.
    Sousa, Ana Isabel
    Silva, Jorge Carvalho
    Ferreira, Isabel M. M.
    Novo, Carlos M. M.
    Borges, Joao Paulo
    CARBOHYDRATE POLYMERS, 2016, 147 : 304 - 312
  • [30] Polysaccharide-Based Nanoparticles for Colon-Targeted Drug Delivery Systems
    De Anda-Flores, Yubia
    Carvajal-Millan, Elizabeth
    Campa-Mada, Alma
    Lizardi-Mendoza, Jaime
    Rascon-Chu, Agustin
    Tanori-Cordova, Judith
    Martinez-Lopez, Ana Luisa
    POLYSACCHARIDES, 2021, 2 (03): : 626 - 647
12345