Iodine- mediated intramolecular amination of ketones: the synthesis of 2-acylindoles and 2-acylindolines by tuning N- protecting groups

被引：63
作者：
Gao, Wen-Chao [1 ]
Jiang, Shan [1 ]
Wang, Ruo-Lin [1 ]
Zhang, Chi [1 ]
机构：
[1] Nankai Univ, State Key Lab Elementoorgan Chem, Res Inst Elementoorgan Chem, Tianjin 300071, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2013年 / 49卷 / 43期
基金：
中国国家自然科学基金;
关键词：
CRYPTOLEPIS-SANGUINOLENTA; CONVENIENT SYNTHESIS; INDOLES; HETEROCYCLIZATION; DERIVATIVES; YLIDES; CYCLIZATION; QUINOLINES; INHIBITORS; PYRROLES;
D O I：
10.1039/c3cc40797g
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A general method for constructing both 2-acylindoles and 2-acylindolines via I-2-mediated intramolecular C-N bond formation is presented, and the selective formation of either 2-acylindoles or 2-acylindolines just depends on the nitrogen protecting groups used in the same substrate skeletons.
引用
收藏
页码：4890 / 4892
页数：3
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