Development of immunosensor using magnetic nanoparticles and circular microchannels in PDMS

被引：19

作者：

Agrawal, Shailaja ^{[1
]}

Paknikar, Kishore ^{[1
]}

Bodas, Dhananjay ^{[1
]}

机构：

[1] Agharkar Res Inst, Ctr Nanobiosci, Pune 411004, Maharashtra, India

来源：

MICROELECTRONIC ENGINEERING | 2014年 / 115卷

关键词：

Circular microfluidics; E; coli; Fluorescence detection; Magnetic concentration; IMMUNOMAGNETIC-SEPARATION;

D O I：

10.1016/j.mee.2013.10.020

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

Here we report development of a magnetic nanoparticles based immunosensor chip comprising of specially designed circular microchannel and embedded miniature permanent magnet. The present process of fabrication allows a rapid and reliable tool to create microchannels with ease and at a low cost. The chip permits easy in-flow capture of bacteria, their visual detection and quantification as demonstrated by Escherichia coli detection. Such a technique enhances capture efficiency and makes quantification of captured antigens simple. (C) 2013 Elsevier B.V. All rights reserved.

引用

页码：66 / 69

页数：4

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