Sesquiterpene lactones from the roots of Lindera strychnifolia

被引：35

作者：

Liu, Qing ^{[1
]}

Ahn, Jong Hoon ^{[1
]}

Kim, Seon Beom ^{[1
]}

Lee, Chul ^{[1
]}

Hwang, Bang Yeon ^{[1
]}

Lee, Mi Kyeong ^{[1
]}

机构：

[1] Chungbuk Natl Univ, Coll Pharm, Cheongju 361763, South Korea

来源：

PHYTOCHEMISTRY | 2013年 / 87卷

基金：

新加坡国家研究基金会;

关键词：

Lindera strychnifolia; Lauraceae; Sesquiterpene; Eudesmane; HSC-T6 Hepatic stellate cells; HEPATIC STELLATE CELLS; ANTIFIBROTIC ACTIVITY; CHLORANTHUS; ACTIVATION; REVERSAL; EXTRACT;

D O I：

10.1016/j.phytochem.2012.11.004

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Phytochemical investigation of the roots of Lindera strychnifolia resulted in the isolation of seven sesquiterpene lactones named linderolide G-M (1-7), together with twelve known sesquiterpenes. The structures and relative configurations of 1-7 were determined through spectroscopic observations, and the absolute configurations were defined by CD analysis. Linderolide G (1) and lindestrene (16) showed cytotoxicity against HSC-T6 hepatic stellate cells. (C) 2012 Elsevier Ltd. All rights reserved.

引用

页码：112 / 118

页数：7

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