Ultra-Low Energy Threshold for Cancer Photothermal Therapy Using Transferrin-Conjugated Gold Nanorods

被引：154
作者：
Li, Jing Liang [1 ]
Day, Daniel [1 ]
Gu, Min [1 ]
机构：
[1] Swinburne Univ Technol, Fac Engn & Ind Sci, Ctr Microphoton, Hawthorn, Vic 3122, Australia
来源：
ADVANCED MATERIALS | 2008年 / 20卷 / 20期
关键词：
D O I：
10.1002/adma.200800941
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Transferrin-conjugated gold nanorods are used for efficient targeting, two-photon imaging, and photothermal therapy of cancer cells under both linearly and circularly polarized femtosecond illuminations. The results show that the effective laser energy threshold for therapy can be reduced to around 10 mJ cm(-2), which is one order of magnitude lower than the medical safety standard level.
引用
收藏
页码：3866 / +
页数：7
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