Usefulness of parathyroid hormone as a predictor of heart failure with preserved ejection fraction

被引：15
作者：
Altay, Hakan [1 ]
Zorlu, Ali [2 ]
Bilgi, Muhammet [1 ]
Erol, Tansel [1 ]
Yilmaz, Mehmet Birhan [3 ]
机构：
[1] Baskent Univ, Fac Med, Dept Cardiol, TR-01250 Adana, Turkey
[2] Bulanik State Hosp, Dept Cardiol, Mus, Turkey
[3] Cumhuriyet Univ, Fac Med, Dept Cardiol, Sivas, Turkey
来源：
BIOMARKERS | 2012年 / 17卷 / 05期
关键词：
Parathyroid hormone; heart failure with preserved ejection fraction; LEFT-VENTRICULAR HYPERTROPHY; PRIMARY HYPERPARATHYROIDISM; NATRIURETIC PEPTIDE; DIAGNOSIS; ECHOCARDIOGRAPHY; MASS;
D O I：
10.3109/1354750X.2012.685182
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Objective: To investigate the relation between parathyroid hormone (PTH) and heart failure with preserved ejection fraction (HF-PEF) in outpatients. Methods: One hundred consecutive patients who had preserved left ventricular (LV) ejection fraction and heart failure (HF) symptoms, were enrolled. Echocardiography, assessing the diastolic functions was performed. Blood samples were collected for intact PTH and brain natriuretic peptide (BNP). Results: Significant correlations between PTH level and predictors of advanced HF-PEF were found (p < 0.05). PTH level and left atrium diameter were found to be independent predictors of DHF. Conclusion: Measurement of serum PTH provides complementary information for the diagnosis and prognosis of HF-PEF.
引用
收藏
页码：447 / 454
页数：8
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