Usefulness of parathyroid hormone as a predictor of heart failure with preserved ejection fraction

被引：15

作者：

Altay, Hakan ^{[1
]}

Zorlu, Ali ^{[2
]}

Bilgi, Muhammet ^{[1
]}

Erol, Tansel ^{[1
]}

Yilmaz, Mehmet Birhan ^{[3
]}

机构：

[1] Baskent Univ, Fac Med, Dept Cardiol, TR-01250 Adana, Turkey

[2] Bulanik State Hosp, Dept Cardiol, Mus, Turkey

[3] Cumhuriyet Univ, Fac Med, Dept Cardiol, Sivas, Turkey

来源：

BIOMARKERS | 2012年 / 17卷 / 05期

关键词：

Parathyroid hormone; heart failure with preserved ejection fraction; LEFT-VENTRICULAR HYPERTROPHY; PRIMARY HYPERPARATHYROIDISM; NATRIURETIC PEPTIDE; DIAGNOSIS; ECHOCARDIOGRAPHY; MASS;

D O I：

10.3109/1354750X.2012.685182

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Objective: To investigate the relation between parathyroid hormone (PTH) and heart failure with preserved ejection fraction (HF-PEF) in outpatients. Methods: One hundred consecutive patients who had preserved left ventricular (LV) ejection fraction and heart failure (HF) symptoms, were enrolled. Echocardiography, assessing the diastolic functions was performed. Blood samples were collected for intact PTH and brain natriuretic peptide (BNP). Results: Significant correlations between PTH level and predictors of advanced HF-PEF were found (p < 0.05). PTH level and left atrium diameter were found to be independent predictors of DHF. Conclusion: Measurement of serum PTH provides complementary information for the diagnosis and prognosis of HF-PEF.

引用

页码：447 / 454

页数：8

共 29 条

[1] Relation of Serum Parathyroid Hormone Level to Severity of Heart Failure
Allay, Hakan
Zorlu, Ali
Binici, Suleyman
Bilgi, Muhammet
Yilmaz, Mehmet Birhan
Colkesen, Yucel
Erol, Tansel
Muderrisoglu, Haldun
[J]. AMERICAN JOURNAL OF CARDIOLOGY, 2012, 109 (02) : 252 - 256
[2] Congestive Heart Failure is a Systemic Illness: A Role for Minerals and Micronutrients
Alsafwah, Shadwan
LaGuardia, Stephen P.
Arroyo, Maximiliano
Dockery, Brian K.
Bhattacharya, Syamal K.
Ahokas, Robert A.
Newman, Kevin P.
[J]. CLINICAL MEDICINE & RESEARCH, 2007, 5 (04) : 238 - 243
[3] AMANN K, 1994, J AM SOC NEPHROL, V4, P1814
[4] Primary hyperparathyroidism and heart disease - a review
Andersson, P
Rydberg, E
Willenheimer, R
[J]. EUROPEAN HEART JOURNAL, 2004, 25 (20) : 1776 - 1787
[5] SITE OF 1,25(OH)2 VITAMIN-D3 SYNTHESIS IN KIDNEY
BRUNETTE, MG
CHAN, M
FERRIERE, C
ROBERTS, KD
[J]. NATURE, 1978, 276 (5685) : 287 - 289
[6] Executive summary of the Third Report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III)
Cleeman, JI
Grundy, SM
Becker, D
Clark, LT
Cooper, RS
Denke, MA
Howard, WJ
Hunninghake, DB
Illingworth, DR
Luepker, RV
McBride, P
McKenney, JM
Pasternak, RC
Stone, NJ
Van Horn, L
Brewer, HB
Ernst, ND
Gordon, D
Levy, D
Rifkind, B
Rossouw, JE
Savage, P
Haffner, SM
Orloff, DG
Proschan, MA
Schwartz, JS
Sempos, CT
Shero, ST
Murray, EZ
[J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2001, 285 (19): : 2486 - 2497
[7] ECHOCARDIOGRAPHIC ASSESSMENT OF LEFT-VENTRICULAR HYPERTROPHY - COMPARISON TO NECROPSY FINDINGS
DEVEREUX, RB
ALONSO, DR
LUTAS, EM
GOTTLIEB, GJ
CAMPO, E
SACHS, I
REICHEK, N
[J]. AMERICAN JOURNAL OF CARDIOLOGY, 1986, 57 (06) : 450 - 458
[8] BNP and NT-proBNP predict echocardiographic severity of diastolic dysfunction
Grewal, Jasmine
McKelvie, Robert
Lonn, Eva
Tait, Peter
Carlsson, Jonas
Gianni, Monica
Jarnert, Christina
Persson, Hans
[J]. EUROPEAN JOURNAL OF HEART FAILURE, 2008, 10 (03) : 252 - 259
[9] Heart failure with preserved left ventricular Systolic function - Epidemiology clinical characteristics and prognosis
Hogg, K
Swedberg, K
McMurray, J
[J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2004, 43 (03) : 317 - 327
[10] The clinical consequences of secondary hyperparathyroidism:: focus on clinical outcomes
Hörl, WH
[J]. NEPHROLOGY DIALYSIS TRANSPLANTATION, 2004, 19 : 2 - 8

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