The ketogenic diet in pharmacoresistant childhood epilepsy

被引：66

作者：

Winesett, Steven Parrish ^{[1
]}

Bessone, Stacey Kordecki ^{[2
]}

Kossoff, Eric H. W. ^{[3
]}

机构：

[1] Univ S Florida, Johns Hopkins Univ, Johns Hopkins All Childrens Hosp, St Petersburg, FL 33701 USA

[2] Johns Hopkins All Childrens Hosp, St Petersburg, FL USA

[3] Johns Hopkins Univ Hosp, Neurol & Pediat, Ketogen Diet Ctr, Pediat Neurol Residency Program, Baltimore, MD 21287 USA

来源：

EXPERT REVIEW OF NEUROTHERAPEUTICS | 2015年 / 15卷 / 06期

关键词：

doose syndrome; epilepsy; GLUT-1; deficiency; infantile spasms; ketogenic; lennox-gastaut syndrome; low glycemic index diet; MCT diet; modified atkins diet; seizures; MYOCLONIC-ASTATIC EPILEPSY; MODIFIED ATKINS DIET; SINGLE-CENTER EXPERIENCE; GLYCEMIC-INDEX TREATMENT; ALTERNATING HEMIPLEGIA; REFRACTORY EPILEPSY; DEFICIENCY SYNDROME; DRAVET SYNDROME; EFFICACY; CHILDREN;

D O I：

10.1586/14737175.2015.1044982

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Available pharmacologic treatments for seizures are limited in their efficacy. For a patient with seizures, pharmacologic treatment with available anticonvulsant medications leads to seizure control in <70% of patients. Surgical resection can lead to control in a select subset of patients but still leaves a significant number of patients with uncontrolled seizures. The ketogenic diet and related diets have proven to be useful in pharmacoresistant childhood epilepsy.

引用

页码：621 / 628

页数：8