Glaucoma, but not cataracts, predicts lower verbal fluency performance: 3.8-year follow-up from the ELSA-Brasil study

被引：0

作者：

Vidal, Kallene S. M. ^{[1
]}

Bertola, Laiss ^{[2
]}

Suemoto, Claudia K. ^{[3
]}

Moreno, Arlinda B. ^{[4
]}

Duncan, Bruce ^{[5
,6
]}

Schmidt, Maria Ines ^{[5
,6
]}

Maestri, Marcelo ^{[7
]}

Barreto, Sandhi M. ^{[8
,9
]}

Lotufo, Paulo A. ^{[2
,10
]}

Bensenor, Isabela M. ^{[2
,10
]}

Brunoni, Andre R. ^{[2
,10
,11
]}

机构：

[1] Univ Sao Paulo, Sao Paulo, Brazil

[2] Univ Sao Paulo, Fac Med, Dept Internal Med, Sao Paulo, Brazil

[3] Univ Sao Paulo, Fac Med, Div Geriatr, Sao Paulo, Brazil

[4] Fundacao Oswaldo Cruz, Natl Sch Publ Hlth, Dept Epidemiol & Quantitat Methods Hlth, Rio De Janeiro, Brazil

[5] Univ Fed Rio Grande do Sul, Postgrad Studies Program Epidemiol, Porto Alegre, RS, Brazil

[6] Univ Fed Rio Grande do Sul, Hosp Clin Porto Alegre, Porto Alegre, RS, Brazil

[7] Univ Rio Grande do Sul, Fac Med, Dept Ophthalmol & Otorhinolaryngol, Porto Alegre, RS, Brazil

[8] Univ Fed Minas Gerais, Fac Med, Belo Horizonte, MG, Brazil

[9] Univ Fed Minas Gerais, Hosp Clin, Belo Horizonte, MG, Brazil

[10] Univ Sao Paulo, Hosp Univ, Ctr Clin & Epidemiol Res, Sao Paulo, Brazil

[11] Univ Sao Paulo, Fac Med, Dept & Inst Psychiat, Lab Neurosci LIM 27, Sao Paulo, Brazil

来源：

AGING NEUROPSYCHOLOGY AND COGNITION | 2021年 / 28卷 / 06期

基金：

巴西圣保罗研究基金会;

关键词：

Cohort study; verbal fluency; glaucoma; cataracts; cognition; eye diseases; OPEN-ANGLE GLAUCOMA; COGNITIVE IMPAIRMENT; ALZHEIMERS-DISEASE; POPULATION; DEMENTIA; QUESTIONNAIRE; PREVALENCE;

D O I：

10.1080/13825585.2020.1837723

中图分类号：

B844 [发展心理学（人类心理学）];

学科分类号：

040202 ;

摘要：

Glaucoma, cataracts, and cognitive decline are most common in older ages. Although cross-sectional studies showed that these disorders are associated, follow-up studies are lacking. To investigate this issue, baseline and follow-up data from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) were employed. We evaluated participants >= 55 years-old at follow-up without diagnosis of dementia, stroke, and other eye conditions except for glaucoma and cataracts. Cognition was evaluated using delayed word recall, verbal fluency, and trail making (version B) tests. Regression models were employed to investigate associations between glaucoma and cognition, adjusted by several confounders. Out of 3,867 participants, 379 and 118 presented cataracts and glaucoma, respectively. Only glaucoma was apredictor of lower verbal fluency (B = -0.23, 95% CI -035 to -012, p< 0.001). Other associations were not significant (ps>0.57). Our results suggest that glaucoma may be related to declining cognition.

引用

页码：871 / 883

页数：13