e-PTSD: an overview on how new technologies can improve prediction and assessment of Posttraumatic Stress Disorder (PTSD)

被引:54
作者
Bourla, Alexis [1 ]
Mouchabac, Stephane [1 ]
El Hage, Wissam [2 ]
Ferreri, Florian [1 ]
机构
[1] Sorbonne Univ, Hop St Antoine, AP HP, Dept Psychiat,Serv Psychiat, F-75012 Paris, France
[2] Univ Francois Rabelais Tours, CHRU Tours, Clin Psychiat Univ, Tours, France
关键词
Posttraumatic stress disorder; digital phenotype; Ecological Momentary Assessment; virtual reality; heart rate variability; new technologies; Artificial Intelligence; TEPT; fenotipo digital; Evaluacion Ecologica Momentanea; realidad virtual; Variabilidad de la frecuencia cardiaca; Nuevas tecnologias; Inteligencia artificial; PTSD; center dot The impact of the new technologies on health professionals practice in PTSD care remains to be determined; center dot We conducted an overview on the technologies used for prediction and assessment of PTSD; center dot This review shows that it is possible to start building the PTSD digital phenotype; center dot These tools must therefore be explained and adapted to the different profiles of physicians and patients; HEART-RATE-VARIABILITY; VIRTUAL-REALITY; BIPOLAR DISORDER; RISK-FACTORS; SELF-REPORT; SYMPTOMS; PLACEBO; TRAUMA; COMORBIDITY; ADULTS;
D O I
10.1080/20008198.2018.1424448
中图分类号
B849 [应用心理学];
学科分类号
040203 ;
摘要
Background: New technologies may profoundly change our way of understanding psychiatric disorders including posttraumatic stress disorder (PTSD). Imaging and biomarkers, along with technological and medical informatics developments, might provide an answer regarding at-risk patient's identification. Recent advances in the concept of digital phenotype', which refers to the capture of characteristics of a psychiatric disorder by computerized measurement tools, is one paradigmatic example.Objective: The impact of the new technologies on health professionals practice in PTSD care remains to be determined. The recent evolutions could disrupt the clinical practices and practitioners in their beliefs, ethics and representations, going as far as questioning their professional culture. In the present paper, we conducted an extensive search to highlight the articles which reflect the potential of these new technologies.Method: We conducted an overview by querying PubMed database with the terms [PTSD] [Posttraumatic stress disorder] AND [Computer] OR [Computerized] OR [Mobile] OR [Automatic] OR [Automated] OR [Machine learning] OR [Sensor] OR [Heart rate variability] OR [HRV] OR [actigraphy] OR [actimetry] OR [digital] OR [motion] OR [temperature] OR [virtual reality].Results: We summarized the synthesized literature in two categories: prediction and assessment (including diagnostic, screening and monitoring). Two independent reviewers screened, extracted data and quality appraised the sources. Results were synthesized narratively.Conclusions: This overview shows that many studies are underway allowing researchers to start building a PTSD digital phenotype using passive data obtained by biometric sensors. Active data obtained from Ecological Momentary Assessment (EMA) could allow clinicians to assess PTSD patients. The place of connected objects, Artificial Intelligence and remote monitoring of patients with psychiatric pathology remains to be defined. These tools must be explained and adapted to the different profiles of physicians and patients. The involvement of patients, caregivers and health professionals is essential to the design and evaluation of these new tools. Contexto: Las nuevas tecnologias podrian cambiar de manera profunda nuestra forma de entender los trastornos psiquiatricos incluyendo el trastorno de estres postraumatico (TEPT). Tecnicas de imagen y biomarcadores, junto con desarrollos en informaticas medicas y tecnologicas, pueden proveer una respuesta en relacion con la identificacion de pacientes en riesgo. Avances recientes en el concepto de genotipo digital', que se refiere a la captura' de las caracteristicas de un trastorno psiquiatrico mediante instrumentos de medicion computarizada, es un ejemplo paradigmatico de todo ello.Objetivo: El impacto de las nuevas tecnologias en la practica de los profesionales de la salud en el ambito del tratamiento del trastorno de estres postraumatico (TEPT), esta aun por determinar. Las evoluciones recientes pueden trastornar o interrumpir tanto las practicas clinicas como a los profesionales que las ejercen. Tambien a sus conceptos eticos y a sus representaciones hasta el punto de poder poner en cuestion su cultura profesional. En este trabajo, hemos realizado una busqueda intensa con el fin de poner de manifiesto los trabajos que mejor reflejan el potencial de estas nuevas tecnologias. Metodo: Hemos realizado una busqueda panoramica en la base de datos PubMed basandonos en titulos hasta Junio de 2017 que contenian los terminos [PTSD] [Posttraumatic stress disorder] AND [Computer] OR [Computerized] OR [Mobile] OR [Automatic] OR [Automated] OR [Machine learning] OR [Sensor] OR [Heart rate variability] OR [HRV] OR [actigraphy] OR [actimetry] OR [digital] OR [motion] OR [temperature] OR [virtual reality]'.Resultados: hemos resumido la literatura sintetizada en dos categorias: prediccion y evaluacion (incluyendo dignostico, discriminacion y monitorizacion). Dos investigadores independientes realizaron el triaje, extrajeron los datos y determinaron la calidad de las fuentes. Los resultados se refieren y sintetizan narrativamente.Conclusiones: este estudio muestra que muchos estudios estan en marcha permitiendo empezar a construir un fenotipo digital de TEPT, usando datos pasivos obtenidos por sensores biometricos. Datos activos obtenidos a traves de una Evaluacion Momentanea Ecologica (EME), puede permitir evaluar a pacientes con TEPT para hacernos una idea de su severidad. El lugar que deben ocupar objetos conectados, inteligencia artificial y monitorizacion remota debe ser aun definido. Para poder ser utilizados, estos instrumentos deben ser por tanto explicados y adaptados a los diferentes perfiles de medicos y pacientes. La participacion de los pacientes, cuidadores y de otros profesionales de la salud es esencial cara a disenar y evaluar estos nuevos instrumentos.PubMed[PTSD] [Posttraumatic stress disorder] AND [Computer] OR [Computerized] OR [Mobile] OR [Automatic] OR [Automated] OR [Machine learning] OR [Sensor] OR [Heart rate variability] OR [HRV] OR [actigraphy] OR [actimetry] OR [digital] OR [motion] OR [temperature] OR [virtual reality]
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