Combining machine learning and matching techniques to improve causal inference in program evaluation

被引:21
作者
Linden, Ariel [1 ,2 ]
Yarnold, Paul R. [3 ,4 ]
机构
[1] Linden Consulting Grp LLC, 1301 North Bay Dr, Ann Arbor, MI 48103 USA
[2] Univ Michigan, Sch Med, Div Gen Med, Ann Arbor, MI USA
[3] Optimal Data Anal LLC, Chicago, IL USA
[4] Univ South Carolina, Coll Pharm, Southern Network Adverse React SONAR, Columbia, SC USA
关键词
balance; causal inference; machine learning; matching; propensity score; PROPENSITY SCORE; DISEASE MANAGEMENT; COVARIATE BALANCE; REGRESSION; MODEL;
D O I
10.1111/jep.12592
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
Rationale, aims and objectivesProgram evaluations often utilize various matching approaches to emulate the randomization process for group assignment in experimental studies. Typically, the matching strategy is implemented, and then covariate balance is assessed before estimating treatment effects. This paper introduces a novel analytic framework utilizing a machine learning algorithm called optimal discriminant analysis (ODA) for assessing covariate balance and estimating treatment effects, once the matching strategy has been implemented. This framework holds several key advantages over the conventional approach: application to any variable metric and number of groups; insensitivity to skewed data or outliers; and use of accuracy measures applicable to all prognostic analyses. Moreover, ODA accepts analytic weights, thereby extending the methodology to any study design where weights are used for covariate adjustment or more precise (differential) outcome measurement. MethodOne-to-one matching on the propensity score was used as the matching strategy. Covariate balance was assessed using standardized difference in means (conventional approach) and measures of classification accuracy (ODA). Treatment effects were estimated using ordinary least squares regression and ODA. ResultsUsing empirical data, ODA produced results highly consistent with those obtained via the conventional methodology for assessing covariate balance and estimating treatment effects. ConclusionsWhen ODA is combined with matching techniques within a treatment effects framework, the results are consistent with conventional approaches. However, given that it provides additional dimensions and robustness to the analysis versus what can currently be achieved using conventional approaches, ODA offers an appealing alternative.
引用
收藏
页码:864 / 870
页数:7
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